Iterons are short, repeated DNA sequences that are important for the replication of circular single-stranded DNA viruses. No tools that can reliably predict iterons are currently available. The CRUcivirus Iteron SEarch (CRUISE) tool is a computational tool that identifies iteron candidates near stem-loop structures in viral genomes.
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Roux, Simon (Ed.)
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Pratt, Alyssa A. ; Torrance, Ellis L. ; Kasun, George W. ; Stedman, Kenneth M. ; de la Higuera, Ignacio ( , Microbiology Resource Announcements)Roux, Simon (Ed.)ABSTRACT Nucleic acid secondary structures play important roles in regulating biological processes. StemLoop-Finder is a computational tool to recognize and annotate conserved structural motifs in large data sets. The program is optimized for the detection of stem-loop structures that may serve as origins of replication in circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses.more » « less