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The overwinter survival mechanisms of Antarctic krill, Euphausia superba , are poorly characterized, especially for juveniles. It has been suggested that juveniles adopt a mix of strategies characteristic of both larvae and adults. Like larvae, they may feed opportunistically throughout winter when food is available, and like adults they may be able to suppress their metabolism when food is scarce. In this study we look at the overwinter strategies of juvenile krill and how their reproductive development changes when energy input exceeds what is necessary for survival. We take a closer look at how the sexual maturation of juvenile krill progresses in response to different environmental conditions throughout the fall and winter. We exposed juvenile Antarctic krill to four different “food environment scenarios”, supplementing them with various diets from May to September 2019 that were representative of environmental conditions that they may encounter in different regions of the Western Antarctic Peninsula during autumn and winter. Each month, we measured the physiology and condition of the krill, and assessed the reproductive development of females. We found that when female juvenile krill have greater energy reserves than what is needed to survive the winter, they will begin to sexually mature. Further, whenmore »there are sufficient levels of the fatty acids eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and 16:4 ( n-1 ), krill are likely to be in a more reproductive advanced stage. However, when lipids, EPA, DHA and 16:4 ( n-1 ) are depleted throughout the winter, juvenile female krill lose their ability to develop reproductively. We also found that sexual development is an energy intensive process that requires high respiration rates in juvenile krill. Furthermore, when juvenile females expend energy maturing, their physiological condition declines. This trade-off between early reproductive development and condition in juvenile female krill has important implications for individual health and population fecundity. Gaining a better understanding of the mechanisms behind juvenile krill winter survival strategies and their consequences will allow us to predict how future change at the western Antarctic Peninsula may affect krill population dynamics, especially in light of a warming climate.« less

In recent years, substantial efforts have been made to understand the implications of climate change on Antarctic krill, Euphausia superba , because of their pivotal role in the Southern Ocean food web and in biogeochemical cycling. Winter is one of the least studied seasons in Antarctica and we have limited understanding about the strategies Antarctic krill use to survive the winter. In particular, data on the winter physiology and condition of juvenile Antarctic krill are severely lacking. From May to September (the austral autumn-winter) of 2019, we maintained juvenile Antarctic krill in large (1,330 L) aquarium tanks at Palmer Station, Antarctica and, at monthly time intervals, measured their physiology and condition. Each tank served as a “food environment scenario”, representing possible food environments the krill may encounter during winter along the Western Antarctic Peninsula. We found that, unlike adults, juvenile krill maintain relatively high respiration rates through the winter and respond positively to increased food concentrations by increasing their ingestion rates. Unlike larval krill, juveniles use lipid stores accumulated during the summer and autumn to sustain themselves through periods of starvation in the winter. We used our empirically derived measurements of physiology and condition to estimate the energy budget andmore »growth potential of juvenile krill during the winter. We found that, given their comparatively high respiration rates, small juvenile krill (20 mg dry weight) would need to encounter food at concentrations of ~ 0.15 mg C L -1 daily to avoid loss of body carbon. Without sufficient lipid reserves, this value increases to ~ 0.54 mg C L -1 , daily. The health of juvenile krill in the wintertime is dependent on their ability to accumulate lipid stores in the summer and autumn and to find sufficient food during the winter. Changes in food availability to Antarctic krill throughout the year may become problematic to juvenile krill in the future. Understanding the variability in the winter energy budget of juvenile Antarctic krill will allow us to improve population models that make assumptions on seasonal growth patterns.« less

We present the average rest-frame spectrum of the final catalog of dusty star-forming galaxies (DSFGs) selected from the South Pole Telescope's SPT-SZ survey and measured with Band 3 of the Atacama Large Millimeter/submillimeter Array. This work builds on the previous average rest-frame spectrum, given in Spilker et al. (2014) for the first 22 sources, and is comprised of a total of 78 sources, normalized by their respective apparent dust masses. The spectrum spans 1.9 <z< 6.9 and covers rest-frame frequencies of 240–800 GHz. Combining this data with low-JCO observations from the Australia Telescope Compact Array, we detect multiple bright line features from¹²CO, [Ci], and H₂O, as well as fainter molecular transitions from¹³CO, HCN, HCO⁺, HNC, CN, H₂O⁺, and CH. We use these detections, along with limits from other molecules, to characterize the typical properties of the interstellar medium (ISM) for these high-redshift DSFGs. We are able to divide the large sample into subsets in order to explore how the average spectrum changes with various galaxy properties, such as effective dust temperature. We find that systems with hotter dust temperatures exhibit differences in the bright¹²CO emission lines, and contain either warmer and more excited dense gas tracers or larger densemore »gas reservoirs. These observations will serve as a reference point to studies of the ISM in distant luminous DSFGs (L_IR> 10¹²L_⊙), and will inform studies of chemical evolution before the peak epoch of star formation atz= 2–3.

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Augmented Reality (AR) is increasingly used in medical applications for visualizing medical information. In this paper, we present an AR-assisted surgical guidance system that aims to improve the accuracy of catheter placement in ventriculostomy, a common neurosurgical procedure. We build upon previous work on neurosurgical AR, which has focused on enabling the surgeon to visualize a patient’s ventricular anatomy, to additionally integrate surgical tool tracking and contextual guidance. Specifically, using accurate tracking of optical markers via an external multi-camera OptiTrack system, we enable Microsoft HoloLens 2-based visualizations of ventricular anatomy, catheter placement, and the information on how far the catheter tip is from its target. We describe the system we developed, present initial hologram registration results, and comment on the next steps that will prepare our system for clinical evaluations.

Much research in healthcare robotics explores ex- tending rehabilitative interventions to the home. However, for adults, little guidance exists on how to translate human-delivered, clinic-based interventions into robot-delivered, home-based ones to support longitudinal interaction. This is particularly problematic for neurorehabilitation, where adults with cognitive impairments require unique styles of interaction to avoid frustration or overstimulation. In this paper, we address this gap by exploring the design of robot-delivered neurorehabilitation interventions for people with mild cognitive impairment (PwMCI). Through a multi-year collaboration with clinical neuropsychologists and PwMCI, we developed robot prototypes which deliver cognitive training at home. We used these prototypes as design probes to understand how participants envision long-term deployment of the intervention, and how it can be contextualized to the lives of PwMCI. We report our findings and specify design patterns and considerations for translating neurorehabilitation interventions to robots. This work will serve as a basis for future endeavors to translate cognitive training and other clinical interventions onto a robot, support longitudinal engagement with home-deployed robots, and ultimately extend the accessibility of longitudinal health interventions for people with cognitive impairments.

This study aimed to provide a review of the current status of the biomimetic adhesives that have the potential for clinical application. Biomimetic materials emulate compounds and properties with a biological origin. They have grown to be more relevant in medical fields due to biocompatibility, low toxicity, and a less damaging impact on the environment. Bonding living tissues has proved to be difficult due to the adverse immune reactions to foreign materials and the wet environment of the damaged area. There is a need for biomimetic adhesives due to the shortcomings of synthetic adhesives and metal tools required for wound closure. Despite differences in developmental approaches and organismal properties, the biomimetic adhesives developed have the potential to be used in wet environments with enough strength to help bond the tissues together without any supporting materials.