skip to main content

Search for: All records

Creators/Authors contains: "Lea, R."

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. Abstract

    As scleractinian coral cover declines in the face of increased frequency in disease outbreaks, future reefs may become dominated by octocorals. Understanding octocoral disease responses and consequences is therefore necessary if we are to gain insight into the future of ecosystem services provided by coral reefs. In Florida, populations of the octocoral Eunicea calyculata infected with Eunicea black disease (EBD) were observed in the field in the fall of 2011. This disease was recognized by a stark, black pigmentation caused by heavy melanization. Histological preparations of E. calyculata infected with EBD demonstrated granular amoebocyte (GA) mobilization, melanin granules inmore »much of the GA population, and the presence of fungal hyphae penetrating coral tissue. Previous transcriptomic analysis also identified immune trade-offs evidenced by increased immune investment at the expense of growth. Our investigation utilized proteogenomic techniques to reveal decreased investment in general cell signaling while increasing energy production for immune responses. Inflammation was also prominent in diseased E. calyculata and sheds light on factors driving the extreme phenotype observed with EBD. With disease outbreaks continuing to increase in frequency, our results highlight new targets within the cnidarian immune system and provide a framework for understanding transcriptomics in the context of an organismal disease phenotype and its protein expression.

    « less
  2. Free, publicly-accessible full text available September 1, 2022
  3. Free, publicly-accessible full text available September 1, 2022
  4. Free, publicly-accessible full text available August 1, 2022
  5. Abstract The coherent photoproduction of $$\mathrm{J}/\psi $$ J / ψ and $${\uppsi '}$$ ψ ′ mesons was measured in ultra-peripheral Pb–Pb collisions at a center-of-mass energy $$\sqrt{s_{\mathrm {NN}}}~=~5.02$$ s NN = 5.02  TeV  with the ALICE detector. Charmonia are detected in the central rapidity region for events where the hadronic interactions are strongly suppressed. The $$\mathrm{J}/\psi $$ J / ψ is reconstructed using the dilepton ( $$l^{+} l^{-}$$ l + l - ) and proton–antiproton decay channels, while for the $${\uppsi '}$$ ψ ′   the dilepton and the $$l^{+} l^{-} \pi ^{+} \pi ^{-}$$ l + l - πmore »+ π - decay channels are studied. The analysis is based on an event sample corresponding to an integrated luminosity of about 233 $$\mu {\mathrm{b}}^{-1}$$ μ b - 1 . The results are compared with theoretical models for coherent $$\mathrm{J}/\psi $$ J / ψ and $${\uppsi '}$$ ψ ′ photoproduction. The coherent cross section is found to be in a good agreement with models incorporating moderate nuclear gluon shadowing of about 0.64 at a Bjorken- x of around $$6\times 10^{-4}$$ 6 × 10 - 4 , such as the EPS09 parametrization, however none of the models is able to fully describe the rapidity dependence of the coherent $$\mathrm{J}/\psi $$ J / ψ cross section including ALICE measurements at forward rapidity. The ratio of $${\uppsi '}$$ ψ ′ to $$\mathrm{J}/\psi $$ J / ψ coherent photoproduction cross sections was also measured and found to be consistent with the one for photoproduction off protons.« less
    Free, publicly-accessible full text available August 1, 2022
  6. Free, publicly-accessible full text available August 1, 2022
  7. Abstract The production of $$\phi $$ ϕ mesons has been studied in pp collisions at LHC energies with the ALICE detector via the dimuon decay channel in the rapidity region $$2.5< y < 4$$ 2.5 < y < 4 . Measurements of the differential cross section $$\mathrm{d}^2\sigma /\mathrm{d}y \mathrm{d}p_{\mathrm {T}}$$ d 2 σ / d y d p T are presented as a function of the transverse momentum ( $$p_{\mathrm {T}}$$ p T ) at the center-of-mass energies $$\sqrt{s}=5.02$$ s = 5.02 , 8 and 13 TeV and compared with the ALICE results at midrapidity. The differential cross sections at $$\sqrt{s}=5.02$$more »s = 5.02 and 13 TeV are also studied in several rapidity intervals as a function of $$p_{\mathrm {T}}$$ p T , and as a function of rapidity in three $$p_{\mathrm {T}}$$ p T intervals. A hardening of the $$p_{\mathrm {T}}$$ p T -differential cross section with the collision energy is observed, while, for a given energy, $$p_{\mathrm {T}}$$ p T spectra soften with increasing rapidity and, conversely, rapidity distributions get slightly narrower at increasing $$p_{\mathrm {T}}$$ p T . The new results, complementing the published measurements at $$\sqrt{s}=2.76$$ s = 2.76 and 7 TeV, allow one to establish the energy dependence of $$\phi $$ ϕ meson production and to compare the measured cross sections with phenomenological models. None of the considered models manages to describe the evolution of the cross section with $$p_{\mathrm {T}}$$ p T and rapidity at all the energies.« less
    Free, publicly-accessible full text available August 1, 2022
  8. Free, publicly-accessible full text available August 1, 2022