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Extracting information from the total matter power spectrum with the precision needed for upcoming cosmological surveys requires unraveling the complex effects of galaxy formation processes on the distribution of matter. We investigate the impact of baryonic physics on matter clustering at z = 0 using a library of power spectra from the Cosmology and Astrophysics with MachinE Learning Simulations project, containing thousands of $(25\, h^{-1}\, {\rm Mpc})^3$ volume realizations with varying cosmology, initial random field, stellar and active galactic nucleus (AGN) feedback strength and subgrid model implementation methods. We show that baryonic physics affects matter clustering on scales $k \gtrsim 0.4\, h\, \mathrm{Mpc}^{-1}$ and the magnitude of this effect is dependent on the details of the galaxy formation implementation and variations of cosmological and astrophysical parameters. Increasing AGN feedback strength decreases halo baryon fractions and yields stronger suppression of power relative to N-body simulations, while stronger stellar feedback often results in weaker effects by suppressing black hole growth and therefore the impact of AGN feedback. We find a broad correlation between mean baryon fraction of massive haloes (M200c > 1013.5 M⊙) and suppression of matter clustering but with significant scatter compared to previous work owing to wider exploration of feedback parameters and cosmic variance effects. We show that a random forest regressor trained on the baryon content and abundance of haloes across the full mass range 1010 ≤ Mhalo/M⊙<1015 can predict the effect of galaxy formation on the matter power spectrum on scales k = 1.0–20.0 $h\, \mathrm{Mpc}^{-1}$.

Feedback from active galactic nuclei and stellar processes changes the matter distribution on small scales, leading to significant systematic uncertainty in weak lensing constraints on cosmology. We investigate how the observable properties of group-scale haloes can constrain feedback’s impact on the matter distribution using Cosmology and Astrophysics with MachinE Learning Simulations (CAMELS). Extending the results of previous work to smaller halo masses and higher wavenumber, k, we find that the baryon fraction in haloes contains significant information about the impact of feedback on the matter power spectrum. We explore how the thermal Sunyaev Zel’dovich (tSZ) signal from group-scale haloes contains similar information. Using recent Dark Energy Survey weak lensing and Atacama Cosmology Telescope tSZ cross-correlation measurements and models trained on CAMELS, we obtain 10 per cent constraints on feedback effects on the power spectrum at $k \sim 5\, h\, {\rm Mpc}^{-1}$. We show that with future surveys, it will be possible to constrain baryonic effects on the power spectrum to $\mathcal {O}(\lt 1~{{\ \rm per\ cent}})$ at $k = 1\, h\, {\rm Mpc}^{-1}$ and $\mathcal {O}(3~{{\ \rm per\ cent}})$ at $k = 5\, h\, {\rm Mpc}^{-1}$ using the methods that we introduce here. Finally, we investigate the impact of feedback on the matter bispectrum, finding that tSZ observables are highly informative in this case.