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  1. Brunet, Johanne (Ed.)
    Abstract Honey bees (Apis mellifera L. Hymeoptera: Apidae) use hydrogen peroxide (synthesized by excreted glucose oxidase) as an important component of social immunity. However, both tolerance of hydrogen peroxide and the production of glucose oxidase in honey is costly. Hydrogen peroxide may also be encountered by honey bees at high concentrations in nectar while foraging, however despite its presence both in their foraged and stored foods, it is unclear if and how bees monitor concentrations of, and their behavioral responses to, hydrogen peroxide. The costs of glucose oxidase production and the presence of hydrogen peroxide in both nectar and honeymore »suggest hypotheses that honey bees preferentially forage on hydrogen peroxide supplemented feed syrups at certain concentrations, and avoid feed syrups supplemented with hydrogen peroxide at concentrations above some tolerance threshold. We test these hypotheses and find that, counter to expectation, honey bees avoid glucose solutions supplemented with field-relevant hydrogen peroxide concentrations and either avoid or don’t differentiate supplemented sucrose solutions when given choice assays. This is despite honey bees showing high tolerance for hydrogen peroxide in feed solutions, with no elevated mortality until concentrations of hydrogen peroxide exceed 1% (v/v) in solution, with survival apparent even at concentrations up to 10%. The behavioral interaction of honey bees with hydrogen peroxide during both within-colony synthesis in honey and when foraging on nectar therefore likely relies on interactions with other indicator molecules, and maybe constrained evolutionarily in its plasticity, representing a constitutive immune mechanism.« less
    Free, publicly-accessible full text available January 1, 2023
  2. Free, publicly-accessible full text available August 1, 2022
  3. We enumerate factorizations of a Coxeter element into arbitrary factors in the complex reflection groups G(d, 1, n) (the wreath product of the symmetric group with a cyclic group) and its subgroup G(d, d, n), applying combinatorial and algebraic methods, respectively. After a change of basis, the coefficients that appear are the same as those that appear in the corresponding enumeration in the symmetric group.
  4. In this paper we describe a virtual reality training simulation designed to help police officers learn use of force policies. Our goal is to test a training simulation prototype by measuring improvements to presence and performance. If successful, this can lead to creating a full-scale virtual reality narrative training simulation. The simulation uses a planner-based experience manager to determine the actions of agents other than the participant. Participants’ actions were logged, physiological data was recorded, and the participants filled out questionnaires. Player knowledge attributes were authored to measure participants’ understanding of teaching materials. We demonstrate that when participants interact withmore »the simulation using virtual reality they experience greater presence than when using traditional screen and keyboard controls. We also demonstrate that participants’ performance improves over repeated sessions.« less
  5. Diégues, M. ; Bäckvall, J.-E. ; Pàmies, O. (Ed.)
    Transition metal catalysts and enzymes are ubiquitous tools for chemical synthesis. Potential benefits of combining complementary properties of these catalysts have driven efforts to create artificial metalloenzymes (ArMs), hybrid constructs comprised of synthetic metal centers embedded within protein scaffolds. This unique composition necessitates the use of synthetic chemistry, bioconjugation methodology, and protein engineering for ArM formation. Despite this challenge, a range of approaches for ArM formation have been developed. This review provides an overview these different approaches and discussion of potential advantages and disadvantages of each.