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Abstract Non-negative matrix factorization and its extensions were applied to various areas (i.e., dimensionality reduction, clustering, etc.). When the original data are corrupted by outliers and noise, most of non-negative matrix factorization methods cannot achieve robust factorization and learn a subspace with binary codes. This paper puts forward a robust semi-supervised non-negative matrix factorization method for binary subspace learning, called RSNMF, for image clustering. For better clustering performance on the dataset contaminated by outliers and noise, we propose a weighted constraint on the noise matrix and impose manifold learning into non-negative matrix factorization. Moreover, we utilize the discrete hashing learning method to constrain the learned subspace, which can achieve a binary subspace from the original data. Experimental results validate the robustness and effectiveness of RSNMF in binary subspace learning and image clustering on the face dataset corrupted by Salt and Pepper noise and Contiguous Occlusion.