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Emerging wearable devices are very attractive and promising in biomedical and healthcare fields because of their biocompatibility for monitoring in situ biomarker-associated signals and external stimulus. Many such devices or systems demand microscale sensors fabricated on curved and flexible hydrogel substrates. However, fabrication of microstructures on such substrates is still challenging because the traditional planar lithography process is not compatible with curved, flexible, and hydrated substrates. Here, we present a shadow-mask-assisted deposition process capable of directly generating metallic microstructures on the curved hydrogel substrate, specifically the contact lens, one of the most popular hydrogel substrates for wearable biomedical applications. In this process, the curved hydrogel substrate is temporarily flattened on a planar surface and metal features are deposited on this substrate through a shadow mask. To achieve a high patterning fidelity, we have experimentally and theoretically investigated various types of distortion due to wrinkles on 3D-printed sample holders, geometric distortion of the substrate due to the flattening process, and volume change of the hydrogel material during the dehydration and hydration processes of the contact lens. Using this method, we have demonstrated fabrication of various titanium pattern arrays on contact lenses with high fidelity and yield.

Abstract Ultrafast movements propelled by springs and released by latches are thought limited to energetic adjustments prior to movement, and seemingly cannot adjust once movement begins. Even so, across the tree of life, ultrafast organisms navigate dynamic environments and generate a range of movements, suggesting unrecognized capabilities for control. We develop a framework of control pathways leveraging the non-linear dynamics of spring-propelled, latch-released systems. We analytically model spring dynamics and develop reduced-parameter models of latch dynamics to quantify how they can be tuned internally or through changing external environments. Using Lagrangian mechanics, we test feedforward and feedback control implementation via spring and latch dynamics. We establish through empirically-informed modeling that ultrafast movement can be controllably varied during latch release and spring propulsion. A deeper understanding of the interconnection between multiple control pathways, and the tunability of each control pathway, in ultrafast biomechanical systems presented here has the potential to expand the capabilities of synthetic ultra-fast systems and provides a new framework to understand the behaviors of fast organisms subject to perturbations and environmental non-idealities.

Global ocean mean salinityis a key indicator of the Earth's hydrological cycle and the exchanges of freshwater between land and ocean, but its determination remains a challenge. Aside from traditional methods based on gridded salinity fields derived from in situ measurements, we explore estimates ofbased on liquid freshwater changes derived from space gravimetry data corrected for sea ice effects. For the 2005–2019 period analyzed, the differentseries show little consistency in seasonal, interannual, and long‐term variability. In situ estimates show sensitivity to choice of product and unrealistic variations. A suspiciously large rise insince ∼2015 is enough to measurably affect halosteric sea level estimates and can explain recent discrepancies in the global mean sea level budget. Gravimetry‐basedestimates are more realistic, inherently consistent with estimated freshwater contributions to global mean sea level, and provide a way to calibrate the in situ estimates.