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The cerebrospinal fluid surrounds the brain and the spinal cord, and is believed to be a potential risk factor to many CNS diseases. The biomechanics of the CSF flow in the brain ventricles is poorly understood due partly to the difficulty in obtaining the flow data in vivo. This paper describes the outcomes of a computational study to examine the elastic response of the walls of the ventricles and its effects on the flow. Comparisons of the simulated results are guided by clinical data obtained with the Time-SLIP MRI, which captures ventricular CSF flows in real time in vivo.more » « less
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