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  1. Abstract The accurate simulation of additional interactions at the ATLAS experiment for the analysis of proton–proton collisions delivered by the Large Hadron Collider presents a significant challenge to the computing resources. During the LHC Run 2 (2015–2018), there were up to 70 inelastic interactions per bunch crossing, which need to be accounted for in Monte Carlo (MC) production. In this document, a new method to account for these additional interactions in the simulation chain is described. Instead of sampling the inelastic interactions and adding their energy deposits to a hard-scatter interaction one-by-one, the inelastic interactions are presampled, independent of the hardmore »scatter, and stored as combined events. Consequently, for each hard-scatter interaction, only one such presampled event needs to be added as part of the simulation chain. For the Run 2 simulation chain, with an average of 35 interactions per bunch crossing, this new method provides a substantial reduction in MC production CPU needs of around 20%, while reproducing the properties of the reconstructed quantities relevant for physics analyses with good accuracy.« less
    Free, publicly-accessible full text available December 1, 2023
  2. The analysis of membranous extracellular vesicles, such as exosomes vesicles (EV) opens a new direction for the rapid disease diagnosis because EVs can carry molecular constituents of their originating cells. Secreted by mammalian cells, the size of most membrane-bound phospholipid EVs ranges from 50 to 150 nm in diameter. Recent studies have demonstrated the potential of using EVs for cancer diagnosis and treatment monitoring. To diagnose infectious diseases using EVs, the ability to discriminate EVs from host cells and parasites is key. Here, we report a rapid EV analysis assay that can discriminate EVs based on a host-specific transmembrane proteinmore »(CD63 antigen) using a label-free optical biosensor.« less
  3. The optical resonances of the silicon nanopost array patterned on a silicon-on-insulator (SOI) substrate have been investigated. The fabricated device supports optical resonances in the range of 1.55 μm with a variable Q factor depending on the angle of incidence. By sealing the device on top of the nanoposts, we demonstrated a lateral flow-through label-free biosensor built on SOI. The biosensor exhibits the refractive index sensitivity of 800 nm/RIU and the femtomolar sensitivity for detection of a breast cancer biomarker (ErbB2).
  4. The Askaryan Radio Array (ARA) is an ultrahigh energy (UHE, >10^17  eV) neutrino detector designed to observe neutrinos by searching for the radio waves emitted by the relativistic products of neutrino-nucleon interactions in Antarctic ice. In this paper, we present constraints on the diffuse flux of ultrahigh energy neutrinos between 1016 and 1021  eV resulting from a search for neutrinos in two complementary analyses, both analyzing four years of data (2013–2016) from the two deep stations (A2, A3) operating at that time. We place a 90% CL upper limit on the diffuse all flavor neutrino flux at 1018  eV of EF(E)=5.6×10^−16  cm^−2 s^−1 sr^−1. This analysismore »includes four times the exposure of the previous ARA result and represents approximately 1/5^th the exposure expected from operating ARA until the end of 2022.« less
  5. Free, publicly-accessible full text available March 1, 2023
  6. Abstract The energy response of the ATLAS calorimeter is measured for single charged pions with transverse momentum in the range $$10more »situ single-particle measurements. The calorimeter response to single-pions is observed to be overestimated by $${\sim }2\%$$ ∼ 2 % across a large part of the $$p_{\text {T}}$$ p T spectrum in the central region and underestimated by $${\sim }4\%$$ ∼ 4 % in the endcaps in the ATLAS simulation. The uncertainties in the measurements are $${\lesssim }1\%$$ ≲ 1 % for $$15« less
    Free, publicly-accessible full text available March 1, 2023
  7. Abstract This paper presents a measurement of the electroweak production of two jets in association with a $$Z\gamma $$ Z γ pair, with the Z boson decaying into two neutrinos. It also presents a search for invisible or partially invisible decays of a Higgs boson with a mass of 125  $$\text {GeV}$$ GeV produced through vector-boson fusion with a photon in the final state. These results use data from LHC proton–proton collisions at $$\sqrt{s}$$ s = 13  $$\text {TeV}$$ TeV collected with the ATLAS detector and corresponding to an integrated luminosity of 139  $$\hbox {fb}^{-1}$$ fb - 1 . Themore »event signature, shared by all benchmark processes considered for the measurements and searches, is characterized by a significant amount of unbalanced transverse momentum and a photon in the final state, in addition to a pair of forward jets. Electroweak $$Z\gamma $$ Z γ production in association with two jets is observed in this final state with a significance of 5.2 (5.1 expected) standard deviations. The measured fiducial cross-section for this process is $$1.31\pm 0.29$$ 1.31 ± 0.29  fb. An observed (expected) upper limit of 0.37 ( $$0.34^{+0.15}_{-0.10}$$ 0 . 34 - 0.10 + 0.15 ) at 95% confidence level is set on the branching ratio of a 125  $$\text {GeV}$$ GeV Higgs boson to invisible particles, assuming the Standard Model production cross-section. The signature is also interpreted in the context of decays of a Higgs boson into a photon and a dark photon. An observed (expected) 95% CL upper limit on the branching ratio for this decay is set at 0.018 ( $$0.017^{+0.007}_{-0.005}$$ 0 . 017 - 0.005 + 0.007 ), assuming the Standard Model production cross-section for a 125  $$\text {GeV}$$ GeV Higgs boson.« less
    Free, publicly-accessible full text available February 1, 2023
  8. Abstract During LHC Run 2 (2015–2018) the ATLAS Level-1 topological trigger allowed efficient data-taking by the ATLAS experiment at luminosities up to 2.1 $$\times $$ × 10 $$^{34}$$ 34  cm $$^{-2}$$ - 2 s $$^{-1}$$ - 1 , which exceeds the design value by a factor of two. The system was installed in 2016 and operated in 2017 and 2018. It uses Field Programmable Gate Array processors to select interesting events by placing kinematic and angular requirements on electromagnetic clusters, jets, $$\tau $$ τ -leptons, muons and the missing transverse energy. It allowed to significantly improve the background event rejection andmore »signal event acceptance, in particular for Higgs and B -physics processes.« less
    Free, publicly-accessible full text available January 1, 2023
  9. Free, publicly-accessible full text available January 1, 2023