Search for: All records

The observed winter Barents-Kara Sea (BKS) sea ice concentration (SIC) has shown a close association with the second empirical orthogonal function (EOF) mode of Eurasian winter surface air temperature (SAT) variability, known as Warm Arctic Cold Eurasia (WACE) pattern. However, the potential role of BKS SIC on this WACE pattern of variability and on its long-term trend remains elusive. Here, we show that from 1979 to 2022, the winter BKS SIC and WACE association is most prominent and statistically significant for the variability at the sub-decadal time scale for 5–6 years. We also show the critical role of the multi-decadal trend in the principal component of the WACE mode of variability for explaining the overall Eurasian winter temperature trend over the same period. Furthermore, a large multi-model ensemble of atmosphere-only experiments from 1979 to 2014, with and without the observed Arctic SIC forcing, suggests that the BKS SIC variations induce this observed sub-decadal variability and the multi-decadal trend in the WACE. Additionally, we analyse the model simulated first or the leading EOF mode of Eurasian winter SAT variability, which in observations, closely relates to the Arctic Oscillation (AO). We find a weaker association of this mode to AO and a statistically significant positive trend in our ensemble simulation, opposite to that found in observation. This contrasting nature reflects excessive hemispheric warming in the models, partly contributed by the modelled Arctic Sea ice loss.

 

Abstract Many fish and marine organisms are responding to our planet’s changing climate by shifting their distribution. Such shifts can drive international conflicts and are highly problematic for the communities and businesses that depend on these living marine resources. Advances in climate prediction mean that in some regions the drivers of these shifts can be forecast up to a decade ahead, although forecasts of distribution shifts on this critical time-scale, while highly sought after by stakeholders, have yet to materialise. Here, we demonstrate the application of decadal-scale climate predictions to the habitat and distribution of marine fish species. We show statistically significant forecast skill of individual years that outperform baseline forecasts 3–10 years ahead; forecasts of multi-year averages perform even better, yielding correlation coefficients in excess of 0.90 in some cases. We also demonstrate that the habitat shifts underlying conflicts over Atlantic mackerel fishing rights could have been foreseen. Our results show that climate predictions can provide information of direct relevance to stakeholders on the decadal-scale. This tool will be critical in foreseeing, adapting to and coping with the challenges of a changing future climate, particularly in the most ocean-dependent nations and communities. 

Key Points The external radiative forcing is the primary driver of the 1979–2013 warming for April–September, with varying decadal warming rates The interdecadal Pacific and Atlantic multidecadal variability intensify/dampen the warming when transitioning to positive/negative phase The combined effects of these factors reproduce the observed varied pace of decadal Arctic troposphere warming during 1979–2013 

Abstract. The main drivers of the continental Northern Hemisphere snow cover are investigated in the 1979–2014 period. Four observational datasets are usedas are two large multi-model ensembles of atmosphere-only simulations with prescribed sea surface temperature (SST) and sea ice concentration (SIC). Afirst ensemble uses observed interannually varying SST and SIC conditions for 1979–2014, while a second ensemble is identical except for SIC witha repeated climatological cycle used. SST and external forcing typically explain 10 % to 25 % of the snow cover variance in modelsimulations, with a dominant forcing from the tropical and North Pacific SST during this period. In terms of the climate influence of the snow coveranomalies, both observations and models show no robust links between the November and April snow cover variability and the atmospheric circulation1 month later. On the other hand, the first mode of Eurasian snow cover variability in January, with more extended snow over western Eurasia, isfound to precede an atmospheric circulation pattern by 1 month, similar to a negative Arctic oscillation (AO). A decomposition of the variabilityin the model simulations shows that this relationship is mainly due to internal climate variability. Detailed outputs from one of the modelsindicate that the western Eurasia snow cover anomalies are preceded by a negative AO phase accompanied by a Ural blocking pattern and astratospheric polar vortex weakening. The link between the AO and the snow cover variability is strongly related to the concomitant role of thestratospheric polar vortex, with the Eurasian snow cover acting as a positive feedback for the AO variability in winter. No robust influence of theSIC variability is found, as the sea ice loss in these simulations only drives an insignificant fraction of the snow cover anomalies, with fewagreements among models. 

Abstract Large ensemble simulations with six atmospheric general circulation models involved are utilized to verify the interdecadal Pacific oscillation (IPO) impacts on the trend of Eurasian winter surface air temperatures (SAT) during 1998–2013, a period characterized by the prominent Eurasia cooling (EC). In our simulations, IPO brings a cooling trend over west-central Eurasia in 1998–2013, about a quarter of the observed EC in that area. The cooling is associated with the phase transition of the IPO to a strong negative. However, the standard deviation of the area-averaged SAT trends in the west EC region among ensembles, driven by internal variability intrinsic due to the atmosphere and land, is more than three times the isolated IPO impacts, which can shadow the modulation of the IPO on the west Eurasia winter climate. 

Abstract Development of an assay to predict response to chemotherapy has remained an elusive goal in cancer research. We report a phenotypic chemosensitivity assay for epithelial ovarian cancer based on Doppler spectroscopy of infrared light scattered from intracellular motions in living three-dimensional tumor biopsy tissue measured in vitro. The study analyzed biospecimens from 20 human patients with epithelial ovarian cancer. Matched primary and metastatic tumor tissues were collected for 3 patients, and an additional 3 patients provided only metastatic tissues. Doppler fluctuation spectra were obtained using full-field optical coherence tomography through off-axis digital holography. Frequencies in the range from 10 mHz to 10 Hz are sensitive to changes in intracellular dynamics caused by platinum-based chemotherapy. Metastatic tumor tissues were found to display a biodynamic phenotype that was similar to primary tissue from patients who had poor clinical outcomes. The biodynamic phenotypic profile correctly classified 90% [88–91% c.i.] of the patients when the metastatic samples were characterized as having a chemoresistant phenotype. This work suggests that Doppler profiling of tissue response to chemotherapy has the potential to predict patient clinical outcomes based on primary, but not metastatic, tumor tissue. 

Abstract To examine the atmospheric responses to Arctic sea-ice variability in the Northern Hemisphere cold season (October to following March), this study uses a coordinated set of large-ensemble experiments of nine atmospheric general circulation models (AGCMs) forced with observed daily-varying sea-ice, sea-surface temperature, and radiative forcings prescribed during the 1979-2014 period, together with a parallel set of experiments where Arctic sea ice is substituted by its climatology. The simulations of the former set reproduce the near-surface temperature trends in reanalysis data, with similar amplitude, and their multi-model ensemble mean (MMEM) shows decreasing sea-level pressure over much of the polar cap and Eurasia in boreal autumn. The MMEM difference between the two experiments allows isolating the effects of Arctic sea-ice loss, which explain a large portion of the Arctic warming trends in the lower troposphere and drives a small but statistically significant weakening of the wintertime Arctic Oscillation. The observed interannual co-variability between sea-ice extent in the Barents-Kara Seas and lagged atmospheric circulation is distinguished from the effects of confounding factors based on multiple regression, and quantitatively compared to the co-variability in MMEMs. The interannual sea-ice decline followed by a negative North Atlantic Oscillation-like anomaly found in observations is also seen in the MMEM differences, with consistent spatial structure but much smaller amplitude. This result suggests that the sea-ice impacts on trends and interannual atmospheric variability simulated by AGCMs could be underestimated, but caution is needed because internal atmospheric variability may have affected the observed relationship. 

High‐sensitivity chemical imaging offers a window to decipher the molecular orchestra inside a living system. Based on vibrational fingerprint signatures, coherent Raman scattering microscopy provides a label‐free approach to map biomolecules and drug molecules inside a cell. Yet, by near‐infrared (NIR) pulse excitation, the sensitivity is limited to millimolar concentration for endogenous biomolecules. Here, the imaging sensitivity of stimulated Raman scattering (SRS) is significantly boosted for retinoid molecules to 34 micromolar via electronic preresonance in the visible wavelength regime. Retinoids play critical roles in development, immunity, stem cell differentiation, and lipid metabolism. By visible preresonance SRS (VP‐SRS) imaging, retinoid distribution in single embryonic neurons and mouse brain tissues is mapped, retinoid storage in chemoresistant pancreatic and ovarian cancers is revealed, and retinoids stored in protein network and lipid droplets ofCaenorahbditis elegansare identified. These results demonstrate VP‐SRS microscopy as an ultrasensitive label‐free chemical imaging tool and collectively open new opportunities of understanding the function of retinoids in biological systems.