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While MOOCs have been widely studied in terms of student engagement and academic performance, the extent to which engagement within MOOCs predict career advancement remains underexplored. Building on prior work, this study investigates how participation in discussion forums, specifically social presence and the use of course-relevant keywords, affects career advancement. Using GPT-assisted content analysis of forum posts, we assess how these engagement factors relate to both achievement during the course and post-course career advancement. Our findings indicate that social presence and use of course-relevant keywords has a positive relationship with course achievement during the MOOC. However, no significant relationship was found between career advancement and either social presence or course-related keywords in discussion forums. These findings suggest that while active engagement in MOOC discussion forums enhances academic achievement, it might not directly translate into career advancement, highlighting a possible disconnect between learning participation in MOOCS and professional outcomes. 

Abstract Serological assays used to estimate the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) often rely on manufacturers’ cutoffs established on the basis of severe cases. We conducted a household-based serosurvey of 4,677 individuals in Chennai, India, from January to May 2021. Samples were tested for SARS-CoV-2 immunoglobulin G (IgG) antibodies to the spike (S) and nucleocapsid (N) proteins. We calculated seroprevalence, defining seropositivity using manufacturer cutoffs and using a mixture model based on measured IgG level. Using manufacturer cutoffs, there was a 5-fold difference in seroprevalence estimated by each assay. This difference was largely reconciled using the mixture model, with estimated anti-S and anti-N IgG seroprevalence of 64.9% (95% credible interval (CrI): 63.8, 66.0) and 51.5% (95% CrI: 50.2, 52.9), respectively. Age and socioeconomic factors showed inconsistent relationships with anti-S and anti-N IgG seropositivity using manufacturer cutoffs. In the mixture model, age was not associated with seropositivity, and improved household ventilation was associated with lower seropositivity odds. With global vaccine scale-up, the utility of the more stable anti-S IgG assay may be limited due to the inclusion of the S protein in several vaccines. Estimates of SARS-CoV-2 seroprevalence using alternative targets must consider heterogeneity in seroresponse to ensure that seroprevalence is not underestimated and correlates are not misinterpreted.