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Abstract The DArk Matter In CCDs at Modane (DAMIC-M) experiment is designed to search for light dark matter (m_χ< 10 GeV/c²) at the Laboratoire Souterrain de Modane (LSM) in France. DAMIC-M will use skipper charge-coupled devices (CCDs) as a kg-scale active detector target. Its single-electron resolution will enable eV-scale energy thresholds and thus world-leading sensitivity to a range of hidden sector dark matter candidates. A DAMIC-M prototype, the Low Background Chamber (LBC), has been taking data at LSM since 2022. The LBC provides a low-background environment, which has been used to characterize skipper CCDs, study dark current, and measure radiopurity of materials planned for DAMIC-M. It also allows testing of various subsystems like readout electronics, data acquisition software, and slow control. This paper describes the technical design and performance of the LBC. 

Presentation slides describing the content of scientific and technical papers are an efficient and effective way to present that work. However, manually generating presentation slides is labor intensive. We propose a method to automatically generate slides for scientific papers based on a corpus of 5000 paper-slide pairs compiled from conference proceedings websites. The sentence labeling module of our method is based on SummaRuNNer, a neural sequence model for extractive summarization. Instead of ranking sentences based on semantic similarities in the whole document, our algorithm measures importance and novelty of sentences by combining semantic and lexical features within a sentence window. Our method outperforms several baseline methods including SummaRuNNer by a significant margin in terms of ROUGE score. 

Comprehending cutaneous lupus Cutaneous lupus erythematosus (CLE) is a disfiguring skin condition that affects most patients with systemic lupus erythematosus (SLE) and can be resistant to treatment even when systemic disease is responsive. Billi et al. analyzed CLE lesions and paired normal-appearing skin biopsies, as well as circulating immune cell subsets, to better understand changes in the skin that drive CLE pathogenesis. Using single-cell RNA sequencing and spatial RNA sequencing, they identified a type I IFN–rich signature in prelesional, normal-looking skin that influenced transcription and cell-cell communication for all major skin cell types. CD16 + dendritic cells, which are associated with SLE, were also shaped by the type I IFN environment, and cells in these sites shifted toward a proinflammatory phenotype. Together, these data provide insights into transcriptional changes in the skin that contribute to CLE pathogenesis. 

PICO bubble chambers have exceptional sensitivity to inelastic dark matter-nucleus interactions due to a combination of their extended nuclear recoil energy detection window from a few keV to O(100 keV) or more and the use of iodine as a heavy target. Inelastic dark matter-nucleus scattering is interesting for studying the properties of dark matter, where many theoretical scenarios have been developed. This study reports the results of a search for dark matter inelastic scattering with the PICO-60 bubble chambers. The analysis reported here comprises physics runs from PICO-60 bubble chambers using CF3I and C3F8. The CF3I run consisted of 36.8 kg of CF3I reaching an exposure of 3415 kg-day operating at thermodynamic thresholds between 7 and 20 keV. The C3F8 runs consisted of 52 kg of C3F8 reaching exposures of 1404 kg-day and 1167 kg-day running at thermodynamic thresholds of 2.45 keV and 3.29 keV, respectively. The analysis disfavors various scenarios, in a wide region of parameter space, that provide a feasible explanation of the signal observed by DAMA, assuming an inelastic interaction, considering that the PICO CF3I bubble chamber used iodine as the target material.