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Self-assembly of a fluorescent virus-like particle for imaging in tissues with high autofluorescence

https://doi.org/10.1039/d3tb00469d

Trashi, Ikeda ; Durbacz, Mateusz Z. ; Trashi, Orikeda ; Wijesundara, Yalini H. ; Ehrman, Ryanne N. ; Chiev, Alyssa C. ; Darwin, Cary B. ; Herbert, Fabian C. ; Gadhvi, Jashkaran ; De Nisco, Nicole J. ; et al ( May 2023 , Journal of Materials Chemistry B)

Qβ VLP simplified assembly approach uses the positively charged Rev tag to interact electrostatically with the negatively charged RNAs. This system exploits the known hairpins produced in the coat protein sequence to template the assembly of the full viral capsid.

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Optical control of neuronal activities with photoswitchable nanovesicles

https://doi.org/10.1007/s12274-022-4853-x

Xiong, Hejian ; Alberto, Kevin A. ; Youn, Jonghae ; Taura, Jaume ; Morstein, Johannes ; Li, Xiuying ; Wang, Yang ; Trauner, Dirk ; Slesinger, Paul A. ; Nielsen, Steven O. ; et al ( January 2023 , Nano Research)

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Molecular Dynamics Simulations of Water Condensation on Surfaces with Tunable Wettability

https://doi.org/10.1021/acs.langmuir.0c00915

Ranathunga, Dineli T. ; Shamir, Alexandra ; Dai, Xianming ; Nielsen, Steven O. ( July 2020 , Langmuir)
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Non-Arrhenius Reaction-Diffusion Kinetics for Protein Inactivation over a Large Temperature Range

https://doi.org/10.1021/acsnano.9b00068

Sarkar, Daipayan ; Kang, Peiyuan ; Nielsen, Steven O. ; Qin, Zhenpeng ( July 2019 , ACS Nano)

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Transient Photoinactivation of Cell Membrane Protein Activity without Genetic Modification by Molecular Hyperthermia

https://doi.org/10.1021/acsnano.9b01993

Kang, Peiyuan ; Li, Xiaoqing ; Liu, Yaning ; Shiers, Stephanie I. ; Xiong, Hejian ; Giannotta, Monica ; Dejana, Elisabetta ; Price, Theodore John ; Randrianalisoa, Jaona ; Nielsen, Steven O. ; et al ( November 2019 , ACS Nano)

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Supramolecular and biomacromolecular enhancement of metal-free magnetic resonance imaging contrast agents

https://doi.org/10.1039/C9SC05510J

Lee, Hamilton ; Shahrivarkevishahi, Arezoo ; Lumata, Jenica L. ; Luzuriaga, Michael A. ; Hagge, Laurel M. ; Benjamin, Candace E. ; Brohlin, Olivia R. ; Parish, Christopher R. ; Firouzi, Hamid R. ; Nielsen, Steven O. ; et al ( February 2020 , Chemical Science)

Many contrast agents for magnetic resonance imaging are based on gadolinium, however side effects limit their use in some patients. Organic radical contrast agents (ORCAs) are potential alternatives, but are reduced rapidly in physiological conditions and have low relaxivities as single molecule contrast agents. Herein, we use a supramolecular strategy where cucurbit[8]uril binds with nanomolar affinities to ORCAs and protects them against biological reductants to create a stable radical in vivo . We further overcame the weak contrast by conjugating this complex on the surface of a self-assembled biomacromolecule derived from the tobacco mosaic virus.
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Site-Selective Nucleation and Size Control of Gold Nanoparticle Photothermal Antennae on the Pore Structures of a Virus

https://doi.org/10.1021/jacs.8b10446

Benjamin, Candace E. ; Chen, Zhuo ; Kang, Peiyuan ; Wilson, Blake A. ; Li, Na ; Nielsen, Steven O. ; Qin, Zhenpeng ; Gassensmith, Jeremiah J. ( November 2018 , Journal of the American Chemical Society)

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Investigation of Controlled Growth of Metal–Organic Frameworks on Anisotropic Virus Particles

https://doi.org/10.1021/acsami.8b01369

Li, Shaobo ; Dharmarwardana, Madushani ; Welch, Raymond P. ; Benjamin, Candace E. ; Shamir, Alexandra M. ; Nielsen, Steven O. ; Gassensmith, Jeremiah J. ( May 2018 , ACS Applied Materials & Interfaces)
Molecular Hyperthermia: Spatiotemporal Protein Unfolding and Inactivation by Nanosecond Plasmonic Heating

https://doi.org/10.1002/smll.201700841

Kang, Peiyuan ; Chen, Zhuo ; Nielsen, Steven O. ; Hoyt, Kenneth ; D'Arcy, Sheena ; Gassensmith, Jeremiah J. ; Qin, Zhenpeng ( September 2017 , Small)