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Abstract Due to the central role played by carbohydrates in a multitude of biological processes, there has been a sustained interest in developing effective glycosylation methods to enable more thorough investigation of their essential functions. Among the myriad technologies available for stereoselective glycoside bond formation, dehydrative glycosylation possesses a distinct advantage given the unique properties of C1‐alcohols such as straightforward preparation, stability, and a general reactivity compatible with a diverse set of reaction conditions. In this Focus Review, a survey of direct dehydrative glycosylations of C1‐alcohols is provided with an emphasis on recent achievements, pervading limitations, mechanistic insights, and applications in total synthesis.more » « less
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Zhu, Feng; O'Neill, Sloane; Rodriguez, Jacob; Walczak, Maciej A. (, Chemistry – A European Journal)
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Zhu, Feng; O'Neill, Sloane; Rodriguez, Jacob; Walczak, Maciej A. (, Angewandte Chemie International Edition)
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