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Abstract A 3-D dosimeter fills the need for treatment plan and delivery verification required by every modern radiation-therapy method used today. This report summarizes a proof-of-concept study to develop a water-equivalent solid 3-D dosimeter that is based on novel radiation-hard scintillating material. The active material of the prototype dosimeter is a blend of radiation-hard peroxide-cured polysiloxane plastic doped with scintillating agent P-Terphenyl and wavelength-shifter BisMSB. The prototype detector was tested with 6 MV and 10 MV x-ray beams at Ohio State University’s Comprehensive Cancer Center. A 3-D dose distribution was successfully reconstructed by a neural network specifically trained for this prototype. This report summarizes the material production procedure, the material’s water equivalency investigation, the design of the prototype dosimeter and its beam tests, as well as the details of the utilized machine learning approach and the reconstructed 3-D dose distributions. 

Abstract In this paper we review the physics opportunities at linear$$\mathrm{e}^{+}\mathrm{e}^{-} $$ $e^{+}{e}^{-}$colliders with a special focus on high centre-of-mass energies and beam polarisation, take a fresh look at the various accelerator technologies available or under development and, for the first time, discuss how a facility first equipped with a technology that is mature today could be upgraded with technologies of tomorrow to reach much higher energies and/or luminosities. In addition, we discuss detectors, alternative collider modes, as well as opportunities for beyond-collider experiments and R&D facilities as part of a linear collider facility (LCF). The material of this paper supports all plans for$$\mathrm{e}^{+}\mathrm{e}^{-} $$ $e^{+}{e}^{-}$linear colliders and the additional opportunities they offer, independently of technology choice or proposed site, as well as R&D for advanced accelerator technologies. This joint perspective on the physics goals, early technologies and upgrade strategies has been developed by the LCVision team based on an initial discussion at LCWS2024 in Tokyo and a follow-up at the LCVision Community Event at CERN in January 2025. It heavily builds on decades of achievements of the global linear collider community, in particular in the context of CLIC and ILC. 

We present the measurement of ${\pi }^{+}$-argon inelastic cross sections using the ProtoDUNE single-phase liquid argon time projection chamber in the incident ${\pi }^{+}$kinetic energy range of 500–800 MeV in multiple exclusive channels (absorption, charge exchange, and the remaining inelastic interactions). The results of this analysis are important inputs to simulations of liquid argon neutrino experiments such as the Deep Underground Neutrino Experiment and the Short Baseline Neutrino program at Fermi National Accelerator Laboratory. They will be employed to improve the modeling of final state interactions within neutrino event generators used by these experiments, as well as the modeling of ${\pi }^{+}$-argon secondary interactions within the liquid argon. This is the first measurement of ${\pi }^{+}$-argon absorption at this kinetic energy range as well as the first ever measurement of ${\pi }^{+}$-argon charge exchange. 

A<sc>bstract</sc> A measurement of the angular structure of inclusive jets and those containing a prompt D⁰meson in proton-proton collisions at the LHC at a center-of-mass energy of 5.02 TeV is presented. The data corresponding to an integrated luminosity of 301 pb⁻¹were collected by the CMS experiment in 2017. Two jet grooming algorithms, late-k_Tand soft drop, are used to study the intrajet radiation pattern using iterative Cambridge-Aachen declustering. The splitting-angle distributions of jets with transverse momentum (p_T) of around 100 GeV, obtained with these two algorithms, show that there is a shift of the distribution for jets containing a prompt D⁰meson with respect to inclusive jets. The suppression of emissions at small angles observed in the late-k_Tgrooming approach is consistent with the dead-cone effect, whereas the similar suppression for splittings selected with the soft-drop algorithm appears to be induced by gluon splitting to charm quark-antiquark pairs at large angles. The measured distributions are corrected to the particle level and can be used to constrain model predictions for the substructure of high-p_Tcharm quark jets. 

The 2x2 Demonstrator, a prototype for the Deep Underground Neutrino Experiment (DUNE) liquid argon (LAr) Near Detector, was exposed to the Neutrinos from the Main Injector (NuMI) neutrino beam at Fermi National Accelerator Laboratory (Fermilab). This detector is a prototype of a new modular design for a liquid argon time-projection chamber (LArTPC), comprising a two-by-two array of four modules, each further segmented into two optically isolated LArTPCs. The 2x2 Demonstrator features a number of pioneering technologies, including a low-profile resistive field shell to establish drift fields, native 3D ionization pixelated imaging, and a high-coverage dielectric light readout system. The 2.4-tonne active mass detector is flanked upstream and downstream by supplemental solid-scintillator tracking planes, repurposed from the MINERvA experiment, which track ionizing particles exiting the argon volume. The antineutrino beam data collected by the detector over a 4.5 day period in 2024 include over 30,000 neutrino interactions in the LAr active volume—the first neutrino interactions reported by a DUNE detector prototype. During its physics-quality run, the 2x2 Demonstrator operated at a nominal drift field of 500 V/cm and maintained good LAr purity, with a stable electron lifetime of approximately 1.25 ms. This paper describes the detector and supporting systems, summarizes the installation and commissioning, and presents the initial validation of collected NuMI beam and off-beam self-triggers. In addition, it highlights observed interactions in the detector volume, including candidate muon antineutrino events. 

The Deep Underground Neutrino Experiment (DUNE) is a next-generation neutrino experiment with a rich physics program that includes searches for the hypothetical phenomenon of proton decay. Utilizing liquid-argon time-projection chamber technology, DUNE is expected to achieve world-leading sensitivity in the proton decay channels that involve charged kaons in their final states. The first DUNE demonstrator, ProtoDUNE Single-Phase, was a 0.77 kt detector that operated from 2018 to 2020 at the CERN Neutrino Platform, exposed to a mixed hadron and electron test-beam with momenta ranging from 0.3 to $7\mathrm{GeV}/\mathrm{c}$. We present a selection of low-energy kaons among the secondary particles produced in hadronic reactions, using data from the 6 and $7\mathrm{GeV}/\mathrm{c}$beam runs. The selection efficiency is 1% and the sample purity 92%. The initial energies of the selected kaon candidates encompass the expected energy range of kaons originating from proton decay events in DUNE (below $\sim 200\mathrm{MeV}$). In addition, we demonstrate the capability of this detector technology to discriminate between kaons and other particles such as protons and muons, and provide a comprehensive description of their energy loss in liquid argon, which shows good agreement with the simulation. These results pave the way for future proton decay searches at DUNE. 

A hot and dense state of nuclear matter, known as the quark-gluon plasma, is created in collisions of ultrarelativistic heavy nuclei. Highly energetic quarks and gluons, collectively referred to as partons, lose energy as they travel through this matter, leading to suppressed production of particles with large transverse momenta ( $p_{\mathrm{T}}$). Conversely, high- $p_{\mathrm{T}}$particle suppression has not been seen in proton-lead collisions, raising questions regarding the minimum system size required to observe parton energy loss. Oxygen-oxygen (OO) collisions examine a region of effective system size that lies between these two extreme cases. The CMS detector at the CERN LHC has been used to quantify charged-particle production in inclusive OO collisions for the first time via measurements of the nuclear modification factor ( $R_{\mathrm{AA}}$). The $R_{\mathrm{AA}}$is derived by comparing particle production to expectations based on proton-proton ( $pp$) data and has a value of unity in the absence of nuclear effects. The data for OO and $pp$collisions at a nucleon-nucleon center-of-mass energy $\sqrt{s_{\mathrm{NN}}}=5.36\mathrm{TeV}$correspond to integrated luminosities of $6.1{\mathrm{nb}}^{-1}$and $1.02{\mathrm{pb}}^{-1}$, respectively. The $R_{\mathrm{AA}}$is below unity with a minimum of $0.69\pm 0.04$around $p_{\mathrm{T}}=6\mathrm{GeV}$. The data exhibit better agreement with theoretical models incorporating parton energy loss as compared to baseline models without energy loss.