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Palladium responsive liposomes for triggered release of aqueous contents

https://doi.org/10.1016/j.bmcl.2023.129215

Chasteen, Jordan L.; Padilla-Coley, Sasha; Li, Dong-Hao; Smith, Bradley D. (March 2023, Bioorganic & Medicinal Chemistry Letters)

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Intracellular fluorescence competition assay for inhibitor engagement of histone deacetylase

https://doi.org/10.1016/j.bmcl.2021.128207

Padilla-Coley, Sasha; Rudebeck, Elley E.; Smith, Bradley D.; Pfeffer, Frederick M. (September 2021, Bioorganic & Medicinal Chemistry Letters)
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Supramolecular capture of highly polar amidosquaraine dye in water with nanomolar affinity and large turn-on fluorescence

https://doi.org/10.1039/d1cc05039g

Dharmarwardana, Madushani; Dempsey, Janel M.; Padilla-Coley, Sasha; Jarvis, Tia S.; Shi, Kejia; Atkinson, Kirk M.; Smith, Bradley D. (December 2021, Chemical Communications)

A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and “turn on” visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage induced by the biomedically important enzyme phospholipase A 2 .
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Supramolecular Loading of a Broad Spectrum of Molecular Guests In Hyperbranched Polytriazole Nanoparticles with Cores Containing Multiple Functional Groups

https://doi.org/10.1021/acs.biomac.0c00151

Padilla-Coley, Sasha; Xu, Hui; Morsby, Janeala; Gao, Haifeng; Smith, Bradley D. (June 2020, Biomacromolecules)

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