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  1. Silk, a popular biomaterial is used as a greener alternative of toxic reducing agent in biocompatible graphene synthesis. However, silk often forms gel uncontrollably due to its heavy chain molecular weight, and faces significant challenges in the reduction, stabilization, and dispersion process of graphene. In this contribution, we report a rapid chemical synthesis approach for a low molecular weight silk-inspired polymer via ring opening and microwave-assisted Diels-Alder aided step-growth polymerizations. This synthetic polymer with periodic sequences of hydrophilic and hydrophobic moieties not only reduces graphene oxide (GO) efficiently but enhances the dispersibility of hydrophobic reduced GO (rGO) in aqueous media. 
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    Free, publicly-accessible full text available July 1, 2024
  2. Randomized clinical trials have been the mainstay of clinical research, but are prohibitively expensive and subject to increasingly difficult patient recruitment. Recently, there is a movement to use real-world data (RWD) from electronic health records, patient registries, claims data and other sources in lieu of or supplementing controlled clinical trials. This process of combining information from diverse sources calls for inference under a Bayesian paradigm. We review some of the currently used methods and a novel non-parametric Bayesian (BNP) method. Carrying out the desired adjustment for differences in patient populations is naturally done with BNP priors that facilitate understanding of and adjustment for population heterogeneities across different data sources. We discuss the particular problem of using RWD to create a synthetic control arm to supplement single-arm treatment only studies. At the core of the proposed approach is the model-based adjustment to achieve equivalent patient populations in the current study and the (adjusted) RWD. This is implemented using common atoms mixture models. The structure of such models greatly simplifies inference. The adjustment for differences in the populations can be reduced to ratios of weights in such mixtures. This article is part of the theme issue ‘Bayesian inference: challenges, perspectives, and prospects’. 
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  5. A<sc>bstract</sc>

    A summary of the constraints from searches performed by the ATLAS collaboration for the electroweak production of charginos and neutralinos is presented. Results from eight separate ATLAS searches are considered, each using 140 fb1of proton-proton data at a centre-of-mass energy of$$ \sqrt{s} $$s= 13 TeV collected at the Large Hadron Collider during its second data-taking run. The results are interpreted in the context of the 19-parameter phenomenological minimal supersymmetric standard model, whereR-parity conservation is assumed and the lightest supersymmetric particle is assumed to be the lightest neutralino. Constraints from previous electroweak, flavour and dark matter related measurements are also considered. The results are presented in terms of constraints on supersymmetric particle masses and are compared with limits from simplified models. Also shown is the impact of ATLAS searches on parameters such as the dark matter relic density and the spin-dependent and spin-independent scattering cross-sections targeted by direct dark matter detection experiments. The Higgs boson andZboson ‘funnel regions’, where a low-mass neutralino would not oversaturate the dark matter relic abundance, are almost completely excluded by the considered constraints. Example spectra for non-excluded supersymmetric models with light charginos and neutralinos are also presented.

     
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    Free, publicly-accessible full text available May 1, 2025
  6. Free, publicly-accessible full text available March 1, 2025
  7. A<sc>bstract</sc>

    A search for pair production of squarks or gluinos decaying via sleptons or weak bosons is reported. The search targets a final state with exactly two leptons with same-sign electric charge or at least three leptons without any charge requirement. The analysed data set corresponds to an integrated luminosity of 139 fb1of proton-proton collisions collected at a centre-of-mass energy of 13 TeV with the ATLAS detector at the LHC. Multiple signal regions are defined, targeting several SUSY simplified models yielding the desired final states. A single control region is used to constrain the normalisation of theWZ+ jets background. No significant excess of events over the Standard Model expectation is observed. The results are interpreted in the context of several supersymmetric models featuring R-parity conservation or R-parity violation, yielding exclusion limits surpassing those from previous searches. In models considering gluino (squark) pair production, gluino (squark) masses up to 2.2 (1.7) TeV are excluded at 95% confidence level.

     
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    Free, publicly-accessible full text available February 1, 2025
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  9. Free, publicly-accessible full text available November 1, 2024