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Abstract The formation of enduring relationships dramatically influences future behavior, promoting affiliation between familiar individuals. How such attachments are encoded to elicit and reinforce specific social behaviors in distinct ethological contexts remains unknown. Signaling via the oxytocin receptor (Oxtr) in the nucleus accumbens (NAc) facilitates social reward as well as pair bond formation between mates in socially monogamous prairie voles^1–9. How Oxtr function influences activity in the NAc during pair bonding to promote affiliative behavior with partners and rejection of other potential mates has not been determined. Using longitudinalin vivofiber photometry in wild-type prairie voles and those lacking Oxtr, we demonstrate that Oxtr function sex-specifically regulates pair bonding behaviors and associated activity in the NAc. Oxtr function influences prosocial behavior in females in a state-dependent manner. Females lacking Oxtr demonstrate reduced prosocial behaviors and lower activity in the NAc during initial chemosensory investigation of novel males. Upon pair bonding, affiliative behavior with partners and neural activity in the NAc during these interactions increase, but these changes do not require Oxtr function. Conversely, males lacking Oxtr display increased prosocial investigation of novel females. Using the altered patterns of behavior and activity in the NAc of males lacking Oxtr during their first interactions with a female, we can predict their future preference for a partner or stranger days later. These results demonstrate that Oxtr function sex-specifically influences the early development of pair bonds by modulating prosociality and the neural processing of sensory cues and social interactions with novel individuals, unmasking underlying sex differences in the neural pathways regulating the formation of long-term relationships. 

ABSTRACT To support experimentation with full-duplex (FD) wireless, we recently integrated two FlexICoN Gen-2 wideband FD radios in the open-access, city-scale NSF PAWR COSMOS testbed. Each integrated FD radio consists of an antenna, a customized Gen-2 RF self-interference (SI) canceller box, a USRP software-defined radio, and a remotely accessible compute node. The RF SI canceller box includes an RF canceller printed circuit board which emulates an integrated circuit implementation based on the technique of frequency-domain equalization. The Gen-2 canceller box can achieve up to 50 dB RF SI cancellation across 20 MHz bandwidth. In this demo, we present the design and implementation of the open-acccess, remotely accessible FD radios that are integrated in the indoor COSMOS Sandbox 2 at Columbia University. We also demonstrate example experiments that are available to researchers, where demo participants can observe the visualized performance of the open-access FD radios 

An SDN controller is developed for both testbed management and experimentation for the optical x-haul network in the COSMOS testbed providing a service-on-demand and reconfigurable platform for 5G wireless experiments coupled with edge cloud services.