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Measurements of beam single-spin asymmetries in semi-inclusive deep-inelastic electron scattering (SIDIS) with positively charged kaons off protons have been performed with 10.6 and 10.2 GeV incident electron beams using the CLAS12 spectrometer at Jefferson Lab. We report an analysis of the electroproduction of positively charged kaons over a large kinematic range of fractional energy, Bjorken $x$, transverse momentum, and photon virtualities $Q^2$ranging from 1 ${\mathrm{GeV}}^2$up to 6 ${\mathrm{GeV}}^2$. This is the first published multidimensionally binned CLAS12 measurement of a kaon SIDIS single-spin asymmetry in the valence quark regime. The data provide constraints on the structure function ratio $F_{LU}^{sin\varphi }/F_{UU}$, where $F_{LU}^{sin\varphi }$is a quantity with a leading twist of twist-3 that can reveal novel aspects of the quark-gluon correlations within the nucleon. The impact of the data on understanding the underlying reaction mechanisms and their kinematic variation is explored using theoretical models for the different contributing twist-3 parton-distribution functions (PDFs) and fragmentation functions (FFs). 

We present the first threefold differential measurement for neutral-pion multiplicity ratios produced in semi-inclusive deep-inelastic electron scattering on carbon, iron, and lead nuclei normalized to deuterium from CLAS at Jefferson Lab. We found that the neutral-pion multiplicity ratio is maximally suppressed for the leading hadrons (energy fraction $z\to$1), suppression varying from 25% in carbon up to 75% in lead. An enhancement of the multiplicity ratio at low $z$and high $p_T^2$is observed, suggesting an interconnection between these two variables. This behavior is qualitatively similar to the previous twofold differential measurement of charged pions by the HERMES Collaboration and, recently, by CLAS Collaboration. The largest enhancement was observed at high $p_T^2$for heavier nuclei, namely, iron and lead, while the smallest enhancement was observed for the lightest nucleus, carbon. This behavior suggests a competition between partonic multiple scattering, which causes enhancement, and hadronic inelastic scattering, which causes suppression. 

Measurements of the polarization observables $\mathrm{\Sigma },\mathbf{P},\mathbf{T},{\mathbf{O}}_{\mathbf{x}},{\mathbf{O}}_{\mathbf{z}}$for the reaction $\vec{\gamma }p\to K_S^0{\mathrm{\Sigma }}^{+}$using a linearly polarized photon beam of energy 1.1 to 2.1 GeV are reported. The measured data provide information on a channel that has not been studied extensively, but is required for a full coupled-channel analysis in the nucleon resonance region. Observables have been simultaneously extracted using likelihood sampling with a Markov-Chain Monte Carlo process. Angular distributions in bins of photon energy $E_{\gamma }$are produced for each polarization observable. $\mathbf{T},{\mathbf{O}}_{\mathbf{x}}$, and ${\mathbf{O}}_{\mathbf{z}}$are first time measurements of these observables in this reaction. The extraction of $\mathrm{\Sigma }$extends the energy range beyond a previous measurement. The measurement of $\mathbf{P}$, the recoil polarization, is consistent with previous measurements. The measured data are shown to be significant enough to affect the estimation of the nucleon resonance parameters when fitted within a coupled-channels model. Published by the American Physical Society2025 

The spin structure functions of the proton and the deuteron were measured during the EG4 experiment at Jefferson Lab in 2006. Data were collected for longitudinally polarized electron scattering off longitudinally polarized NH3 and ND3 targets, for Q2 values as small as 0.012 and 0.02 GeV2, respectively, using the CEBAF Large Acceptance Spectrometer. This is the archival paper of the EG4 experiment that summarizes the previously reported results of the polarized structure functions g1, A1F1, and their moments 1, γ0, and ITT, for both the proton and the deuteron. In addition, we report on new results on the neutron g1 extracted by combining proton and deuteron data and correcting for Fermi smearing, and on the neutron moments 1, γ0, and ITT formed directly from those of the proton and the deuteron. Our data are in good agreement with the Gerasimov-Drell-Hearn sum rule for the proton, deuteron, and neutron. Furthermore, the isovector combination was formed for g1 and the Bjorken integral p−n 1 ,andit was compared to available theoretical predictions. All of our results, to the best of our knowledge, provide for the first time extensive tests of spin observable predictions from chiral effective field theory (χEFT) in a Q2 range commensurate with the pion mass. They motivate further improvement in χEFT calculations from other approaches such as the lattice gauge method. 

The biological membrane is an efficient barrier against water-soluble substances. Solute transporters circumvent this membrane barrier by transporting water-soluble solutes across the membrane to the other sides. These transport proteins are thus required for all living organisms. Microorganisms, such as bacteria, effectively exploit solute transporters to acquire useful nutrients for growth or to expel substances that are inhibitory to their growth. Overall, there are distinct types of related solute transporters that are grouped into families or superfamilies. Of these various transporters, the major facilitator superfamily (MFS) represents a very large and constantly growing group and are driven by solute- and ion-gradients, making them passive and secondary active transporters, respectively. Members of the major facilitator superfamily transport an extreme variety of structurally different substrates such as antimicrobial agents, amino acids, sugars, intermediary metabolites, ions, and other small molecules. Importantly, bacteria, especially pathogenic ones, have evolved multidrug efflux pumps which belong to the major facilitator superfamily. Furthermore, members of this important superfamily share similar primary sequences in the form of highly conserved sequence motifs that confer useful functional properties during transport. The transporters of the superfamily also share similarities in secondary structures, such as possessing 12- or 14-membrane spanning α-helices and the more recently described 3-helix structure repeat element, known as the MFS fold. The three-dimensional structures of bacterial multidrug efflux pumps have been determined for only a few members of the superfamily, all drug pumps of which are surprisingly from Escherichia coli. This review briefly summarizes the structural properties of the bacterial multidrug efflux pumps of the major facilitator superfamily in a comparative manner and provides future directions for study. 

Measuring deeply virtual Compton scattering (DVCS) on the neutron is one of the necessary steps to understand the structure of the nucleon in terms of generalized parton distributions (GPDs). Neutron targets play a complementary role to transversely polarized proton targets in the determination of the GPD $E$. This poorly known and poorly constrained GPD is essential to obtain the contribution of the quarks’ angular momentum to the spin of the nucleon. DVCS on the neutron was measured for the first time selecting the exclusive final state by detecting the neutron, using the Jefferson Lab longitudinally polarized electron beam, with energies up to 10.6 GeV, and the CLAS12 detector. The extracted beam-spin asymmetries, combined with DVCS observables measured on the proton, allow a clean quark-flavor separation of the imaginary parts of the Compton form factors $\mathcal{H}$and $\mathcal{E}$. Published by the American Physical Society2024 

The single-differential and fully integrated cross sections for quasifree π+π− electroproduction off protons bound in deuterium have been extracted for the first time. The experimental data were collected at Jefferson Laboratory with the CLAS detector. The measurements were performed in the kinematic region of the invariant mass W from 1.3 to 1.825 GeV and the photon virtuality Q2 from 0.4 to 1.0 GeV2. Sufficient experimental statistics allowed for narrow binning in all kinematic variables, while maintaining a small statistical uncertainty. The extracted cross sections were compared with the corresponding cross sections off free protons, which allowed us to obtain an estimate of the contribution from events in which interactions between the final-state hadrons and the spectator neutron took place. 

The EIC Comprehensive Chromodynamics Experiment (ECCE) detector has been designed to address the full scope of the proposed Electron Ion Collider (EIC) physics program as presented by the National Academy of Science and provide a deeper understanding of the quark–gluon structure of matter. To accomplish this, the ECCE detector offers nearly acceptance and energy coverage along with excellent tracking and particle identification. The ECCE detector was designed to be built within the budget envelope set out by the EIC project while simultaneously managing cost and schedule risks. This detector concept has been selected to be the basis for the EIC project detector.