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Abstract Environmental seismic disturbances limit the sensitivity of LIGO gravitational wave detectors. Trains near the LIGO Livingston detector produce low frequency (0.5– 10   H z ) ground noise that couples into the gravitational wave sensitive frequency band (10– 100   H z ) through light reflected in mirrors and other surfaces. We investigate the effect of trains during the Advanced LIGO third observing run, and propose a method to search for narrow band seismic frequencies responsible for contributing to increases in scattered light. Through the use of the linear regression tool Lasso (least absolute shrinkage and selection operator) and glitch correlations, we identify the most common seismic frequencies that correlate with increases in detector noise as 0.6– 0.8   H z , 1.7– 1.9   H z , 1.8– 2.0   H z , and 2.3– 2.5   H z in the LIGO Livingston corner station. 

Previous work demonstrated an accelerated in vitro and in vivo wound healing response when insulinoma cells were used to deliver insulin to scratches in keratinocyte mono- layers and chronic diabetic excise wounds in mice, respectively. When combined with mesenchymal stem cells (MSCs), the response was amplified (healing in 14 vs. 35+ days). To isolate the role of insulin in the response and exclude any potential contribution of an unknown cancer moiety released by the insulinoma cells, the effect on wound healing of multiple lines derived from the same insulinoma was examined. 

Previous work demonstrated an accelerated in vitro and in vivo wound healing response when insulinoma cells were used to deliver insulin to scratches in keratinocyte mono- layers and chronic diabetic excise wounds in mice, respectively. When combined with mesenchymal stem cells (MSCs), the response was amplified (healing in 14 vs. 35+ days). To isolate the role of insulin in the response and exclude any potential contribution of an un known cancer moiety released by the insulinoma cells, the effect on wound healing of multiple lines derived from the same insulinoma was examined. 

Abstract Rotating nonaxisymmetric neutron stars (NSs) are promising sources for continuous gravitational waves (CWs). CWs may, if detected, inform us about the internal structure and equation of state of NSs. Here, we present a narrowband search for CWs from known pulsars, for which a matched-filter search can be applied. Narrowband searches are robust to mismatches between electromagnetic (EM) and gravitational emissions, in contrast to fully targeted searches where they are assumed to be phase-locked. In this work, we search for the CW counterparts emitted by 34 pulsars using data from the first and second parts of the fourth LIGO–Virgo–KAGRA observing run. We use the 5n-vector narrowband pipeline, which applies frequency-domain matched filtering. In previous searches, it covered a narrow range in the frequency—frequency time derivative (f— $\dot{f}$) space. Here, we also explore a range in the second time derivative of the frequency $\ddot{f}$around the EM observations. Additionally, for the first time, we target sources in a binary system with this kind of search. We find no evidence for CWs and therefore set upper limits on the strain amplitude emitted by each pulsar. For 20 analyses, we report an upper limit below the theoretical spin-down limit. The tightest constraint is for pulsar PSR J0534+2200 (the Crab pulsar), for which our strain upper limit on the CW amplitude corresponds to ≤0.04% of the spin-down power being radiated in the CW channel. 

Abstract We detail the population properties of binary neutron star, neutron star–black hole binary, and binary black hole mergers using 158 events from the cumulative Gravitational-Wave Transient Catalog 4.0. The black hole primary mass distribution consists of a power-law-like continuum that steepens above 35M_⊙with overdensities at 10M_⊙and 35M_⊙. Binary black holes with primary masses near 10M_⊙are more likely to have less massive secondaries, with a mass ratio distribution peaking at $q=0.71_{-0.11}^{+0.12}$, potentially a signature of stable mass transfer during binary evolution. Black hole spins are inferred to be nonextremal, with 90% of black holes havingχ < 0.6, and preferentially aligned with binary orbits, implying many merging binaries form in isolation. However, we find that a significant fraction, 0.23–0.41, of binaries have negative effective inspiral spins, suggesting many could be formed dynamically in gas-free environments. We find evidence for correlation between effective inspiral spin and mass ratio, driven either by variation in the mode of the distribution or the width. The binary black hole merger rate increases with redshift, consistent with the cosmic star formation density. While there is no evidence of the mass spectrum evolving with redshift, the distribution of effective inspiral spin is found to broaden as redshift increases out toz ≈ 1. We infer the local merger rates (atz= 0) to be 8.8–250 Gpc⁻³yr⁻¹for binary neutron stars, 9.3–86 Gpc⁻³yr⁻¹for neutron star–black hole binaries, and 13–26 Gpc⁻³yr⁻¹for binary black holes; all values reflect central 90% credible intervals. 

The angular distribution of gravitational-wave power from persistent sources may exhibit anisotropies arising from the large-scale structure of the Universe. This motivates directional searches for astrophysical and cosmological gravitational-wave backgrounds, as well as continuous-wave emitters. We present results of such a search using data from the first observing run through the first portion of the fourth observing run of the LIGO-Virgo-KAGRA Collaborations. We apply gravitational-wave radiometer techniques to generate skymaps and search for both narrowband and broadband persistent gravitational-wave sources. Additionally, we use spherical harmonic decomposition to probe spatially extended sources. No evidence of persistent gravitational-wave signals is found, and we set the most stringent constraints to date on such emissions. For narrowband point sources, our sensitivity estimate to effective strain amplitude lies in the range $\left(0.03–8.4\right)\times {10}^{-24}$across all-sky and frequency range ( $20-160$) Hz. For targeted sources—Scorpius X-1, SN 1987A, the Galactic Center, Terzan 5, and NGC 6397—we constrain the strain amplitude with best limits ranging from $\sim 1.1\times {10}^{-25}$to $6.5\times {10}^{-24}$. For persistent broadband sources, we constrain the gravitational-wave flux $F_{\alpha ,\hat{n}}^{95\%,\mathrm{UL}}\left(25\mathrm{Hz}\right)<\left(0.008–5.5\right)\times {10}^{-8}\mathrm{erg}{\mathrm{cm}}^{-2}{\mathrm{s}}^{-1}{\mathrm{Hz}}^{-1}$, depending on the sky direction $\hat{n}$and spectral index $\alpha =0,2/3$, 3. Finally, for extended sources, we place upper limits on the angular power spectrum $C_{\ell }^{1/2}<\left(0.63–17\right)\times {10}^{-10}{\mathrm{sr}}^{-1}$. 

Abstract Among known neutron stars, the Vela pulsar is one of the best targets for gravitational-wave searches. It is also one of the most prolific in terms of glitches, which are sudden frequency changes in a pulsar’s rotation. Such glitches could cause a variety of transient gravitational-wave signals. Here, we search for signals associated with a Vela glitch on 2024 April 29 in data of the two LIGO detectors from the fourth LIGO–Virgo–KAGRA observing run. We search both for seconds-scale burst-like emission, primarily from fundamental (f-)mode oscillations, and for longer quasi-monochromatic transients up to 4 months in duration, primarily from quasi-static quadrupolar deformations. We find no significant detection candidates, but for the first time we set direct observational upper limits on gravitational strain amplitude that are stricter than what can be indirectly inferred from the overall glitch energy scale. We discuss the short- and long-duration observational constraints in the context of specific emission models. These results demonstrate the potential of gravitational-wave probes of glitching pulsars as detector sensitivity continues to improve. 

Abstract LIGO, Virgo, and KAGRA form a network of gravitational-wave observatories. Data and analysis results from this network are made publicly available through the Gravitational Wave Open Science Center. This paper describes open data from this network, including the addition of data from the first part of the fourth observing run and selected periods from the preceding engineering run, collected from 2023 May to 2024 January. The public dataset includes calibrated strain time series for each instrument, data from additional channels used for noise subtraction and detector characterization, and analysis data products from version 4.0 of the Gravitational-Wave Transient Catalog. 

Abstract Version 4.0 of the Gravitational-Wave Transient Catalog (GWTC-4.0) adds new candidates detected by the LIGO, Virgo, and KAGRA observatories through the first part of the fourth observing run (O4a: 2023 May 24 15:00:00 to 2024 January 16 16:00:00 UTC) and a preceding engineering run. In these new data, we find 128 compact binary coalescence candidates that are identified by at least one of our search algorithms with a probability of astrophysical originp_astro≥ 0.5 and that are not vetoed during event validation. We also provide detailed source property measurements for 86 of these that have a false-alarm rate <1 yr⁻¹. Based on the inferred component masses, these candidates are consistent with signals from binary black holes (BBHs) and neutron star–black hole binaries (GW230518_125908 and GW230529_181500). Median-inferred component masses of BBHs in the catalog now range from 5.79M⊙ (GW230627_015337) to 137 $M_{\odot }$(GW231123_135430), while GW231123_135430 was probably produced by the most massive binary observed in the catalog. For the first time, we have discovered BBH signals with network signal-to-noise ratio exceeding 30, GW230814_230901 and GW231226_101520, enabling high-fidelity studies of the waveforms and astrophysical properties of these systems. Combined with the 90 candidates included in GWTC-3.0, the catalog now contains 218 candidates withp_astro≥ 0.5 and not otherwise vetoed, more than doubling the size of the catalog and further opening our view of the gravitational-wave Universe.