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The demand for ‘local food’ by U.S. consumers has grown markedly over the last several decades, accompanied by confusion over how to define local food. Is ‘local’ food defined by the location of the farm, food processing factory, distribution warehouse, or all three? Is ‘local’ food defined by geographic, political, or biophysical boundaries? Is ‘local’ solely farm-to-table or can it include factories? This study evaluates food commodity flow ‘localness’ using jurisdictional boundaries and physical distance to investigate the potential for food system transformation and the tradeoffs inherent to ‘localizing’ food production. We take a supply chain approach by making data-driven distinctions between farm-based flows of food and industrial, energy and nonfood (IENF) crops, and manufacturing/distribution flows of food and agriculturally-derived industrial inputs. We analyze the diversity, distance (a proxy for environmental impact), political boundaries, population, weight, and price (net selling value) of food commodity flows. The diversity of a community's food supply has an optimal range of zero to four-hundred miles. We find tradeoffs between food system diversity and local food sourcing, sustainability, and self-sufficiency. As communities look to improve food system resilience, they will need to balance food-miles and the other values associated with local food.more » « less
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The gut is a well-established route of infection and target for viral damage by SARSCoV-2. This is supported by the clinical observation that about half of COVID-19 patients exhibit gastrointestinal (GI) symptoms. We asked whether the analysis of plasma could provide insight into gut barrier dysfunction in patients with COVID-19 infection. Plasma samples of COVID-19 patients (n=30) and healthy control (n=16) were collected during hospitalization. Plasma microbiome was analyzed using 16S rRNA sequencing, metatranscriptomic analysis, and gut permeability markers including FABP-2, PGN and LPS in both patient cohorts. Almost 65% (9 out 14) COVID-19 patients showed abnormal presence of gut microbes in their bloodstream. Plasma samples contained predominately Proteobacteria, Firmicutes, and Actinobacteria. The abundance of gram-negative bacteria (Acinetobacter, Nitrospirillum, Cupriavidus, Pseudomonas, Aquabacterium, Burkholderia, Caballeronia, Parabhurkholderia, Bravibacterium, and Sphingomonas) was higher than the gram-positive bacteria (Staphylococcus and Lactobacillus) in COVID-19 subjects. The levels of plasma gut permeability markers FABP2 (1282±199.6 vs 838.1±91.33; p=0.0757), PGN (34.64±3.178 vs 17.53±2.12; p<0.0001), and LPS (405.5±48.37 vs 249.6±17.06; p=0.0049) were higher in COVID-19 patients compared to healthy subjects. These findings support that the intestine may represent a source for bacteremia and may contribute to worsening COVID-19 outcomes. Therapies targeting the gut and prevention of gut barrier defects may represent a strategy to improve outcomes in COVID19 patients.more » « less
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In early 2020, an international team set out to investigate trade wind cumulus and their coupling to the large-scale circulation through the field campaign EUREC4A: ElUcidating the RolE of Clouds‐Circulation Coupling in ClimAte. Focused on the western tropical Atlantic near Barbados, EUREC4A deployed a number of innovative measurement strategies, including a large network of water isotopic collections, to study the tropical shallow convective environment. The goal of the isotopic measurements was to elucidate processes that regulate the hydroclimate state – for example, by identifying moisture sources, quantifying mixing between atmospheric layers, characterizing the microphysics that influence the formation and persistence of clouds and precipitation, and providing an extra constraint in the evaluation of numerical simulations. During EUREC4A, researchers deployed seven water vapor isotopic analyzers on two aircraft, on three ships, and at the Barbados Cloud Observatory (BCO).more » « less
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Abstract Aerosols interact with radiation and clouds. Substantial progress made over the past 40 years in observing, understanding, and modeling these processes helped quantify the imbalance in the Earth's radiation budget caused by anthropogenic aerosols, called aerosol radiative forcing, but uncertainties remain large. This review provides a new range of aerosol radiative forcing over the industrial era based on multiple, traceable, and arguable lines of evidence, including modeling approaches, theoretical considerations, and observations. Improved understanding of aerosol absorption and the causes of trends in surface radiative fluxes constrain the forcing from aerosol‐radiation interactions. A robust theoretical foundation and convincing evidence constrain the forcing caused by aerosol‐driven increases in liquid cloud droplet number concentration. However, the influence of anthropogenic aerosols on cloud liquid water content and cloud fraction is less clear, and the influence on mixed‐phase and ice clouds remains poorly constrained. Observed changes in surface temperature and radiative fluxes provide additional constraints. These multiple lines of evidence lead to a 68% confidence interval for the total aerosol effective radiative forcing of ‐1.6 to ‐0.6 W m−2, or ‐2.0 to ‐0.4 W m−2with a 90% likelihood. Those intervals are of similar width to the last Intergovernmental Panel on Climate Change assessment but shifted toward more negative values. The uncertainty will narrow in the future by continuing to critically combine multiple lines of evidence, especially those addressing industrial‐era changes in aerosol sources and aerosol effects on liquid cloud amount and on ice clouds.