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None (Ed.)The geographical range of schistosomiasis is affected by the ecology of schistosome parasites and their obligate host snails, including their response to temperature. Previous models predicted schistosomiasis’ thermal optimum at 21.7°C, which is not compatible with the temperature in sub-Saharan Africa (SSA) regions where schistosomiasis is hyperendemic. We performed an extensive literature search for empirical data on the effect of temperature on physiological and epidemiological parameters regulating the free-living stages of S. mansoni and S. haematobium and their obligate host snails, i.e., Biomphalaria spp. and Bulinus spp., respectively. We derived nonlinear thermal responses fitted on these data to parameterize a mechanistic, process-based model of schistosomiasis. We then re-cast the basic reproduction number and the prevalence of schistosome infection as functions of temperature. We found that the thermal optima for transmission of S. mansoni and S. haematobium range between 23.1–27.3°C and 23.6–27.9°C (95% CI) respectively. We also found that the thermal optimum shifts toward higher temperatures as the human water contact rate increases with temperature. Our findings align with an extensive dataset of schistosomiasis prevalence in SSA. The refined nonlinear thermal-response model developed here suggests a more suitable current climate and a greater risk of increased transmission with future warming for more than half of the schistosomiasis suitable regions with mean annual temperature below the thermal optimum.more » « less
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SAGE3 is software to augment the cyberinfrastructure-enhanced research and education enterprise by supporting data-intensive collaboration across a wide range of display devices from high-resolution display walls to laptops. This paper provides insight into SAGE3’s implementation, which significantly improves on prior generations of SAGE by leveraging emerging advancements in Web technologies and Artificial Intelligence. We also provide an overview of new usage patterns that we observed with SAGE3.more » « less
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SAGE3 is software to augment the cyberinfrastructure-enhanced research and education enterprise by supporting data-intensive collaboration across a wide range of display devices from high-resolution display walls to laptops. This paper provides insight into SAGE3’s implementation, which significantly improves on prior generations of SAGE by leveraging emerging advancements in Web technologies and Artificial Intelligence. We also provide an overview of new usage patterns that we observed with SAGE3.more » « less
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SAGE3 is software to augment the cyberinfrastructure-enhanced research and education enterprise by supporting data-intensive collaboration across a wide range of display devices from high-resolution display walls to laptops. This paper provides insight into SAGE3’s implementation, which significantly improves on prior generations of SAGE by leveraging emerging advancements in Web technologies and Artificial Intelligence. We also provide an overview of new usage patterns that we observed with SAGE3.more » « less
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Abstract Adsorption-induced deformation is a change in geometrical dimensions of an adsorbent material caused by gas or liquid adsorption on its surface. This phenomenon is universal and sensitive to adsorbent properties, which makes its prediction a challenging task. However, the pure academic interest is complemented by its importance in a number of engineering applications with porous materials characterization among them. Similar to classical adsorption-based characterization methods, the deformation-based ones rely on the quality of the underlying theoretical framework. This fact stimulates the recent development of qualitative and quantitative models toward the more detailed description of a solid material, e.g. account of non-convex and corrugated pores, calculations of adsorption stress in realistic three-dimension solid structures, the extension of the existing models to new geometries, etc. The present review focuses on the theoretical description of adsorption-induced deformation in micro and mesoporous materials. We are aiming to cover recent theoretical works describing the deformation of both ordered and disordered porous bodies.more » « less
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