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Free, publicly-accessible full text available July 1, 2023
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Free, publicly-accessible full text available July 1, 2023
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Segmenting 3D cell nuclei from microscopy image volumes is critical for biological and clinical analysis, enabling the study of cellular expression patterns and cell lineages. However, current datasets for neuronal nuclei usually contain volumes smaller than 0.01 cubic mm with fewer than 500 instances per volume, unable to reveal the complexity in large brain regions and restrict the investigation of neuronal structures. In this paper, we have pushed the task forward to the sub-cubic millimeter scale and curated the NucMM dataset with two fully annotated volumes: one 0.1 cubic mm electron microscopy (EM) volume containing nearly the entire zebra sh brainmore »
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The Lagrangian method—where current location and intensity are determined by tracking the movement of flow along its path—is the oldest technique for measuring the ocean circulation. For centuries, mariners used compilations of ship drift data to map out the location and intensity of surface currents along major shipping routes of the global ocean. In the mid‐20th century, technological advances in electronic navigation allowed oceanographers to continuously track freely drifting surface buoys throughout the ice‐free oceans and begin to construct basin‐scale, and eventually global‐scale, maps of the surface circulation. At about the same time, development of acoustic methods to track neutrallymore »