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  1. Abstract

    Filamentary structures in neutral hydrogen (Hi) emission are well aligned with the interstellar magnetic field, so Hiemission morphology can be used to construct templates that strongly correlate with measurements of polarized thermal dust emission. We explore how the quantification of filament morphology affects this correlation. We introduce a new implementation of the Rolling Hough Transform (RHT) using spherical harmonic convolutions, which enables efficient quantification of filamentary structure on the sphere. We use this Spherical RHT algorithm along with a Hessian-based method to construct Hi-based polarization templates. We discuss improvements to each algorithm relative to similar implementations in the literature and compare their outputs. By exploring the parameter space of filament morphologies with the Spherical RHT, we find that the most informative Histructures for modeling the magnetic field structure are the thinnest resolved filaments. For this reason, we find a ∼10% enhancement in theB-mode correlation with polarized dust emission with higher-resolution Hiobservations. We demonstrate that certain interstellar morphologies can produce parity-violating signatures, i.e., nonzeroTBandEB, even under the assumption that filaments are locally aligned with the magnetic field. Finally, we demonstrate thatBmodes from interstellar dust filaments are mostly affected by the topology of the filaments with respect to one another and their relative polarized intensities, whereasEmodes are mostly sensitive to the shapes of individual filaments.

     
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  2. We describe the newest generation of the SLAC Microresonator RF (SMuRF) electronics, a warm digital control and readout system for microwave-frequency resonator-based cryogenic detector and multiplexer systems, such as microwave superconducting quantum interference device multiplexers (μmux) or microwave kinetic inductance detectors. Ultra-sensitive measurements in particle physics and astronomy increasingly rely on large arrays of cryogenic sensors, which in turn necessitate highly multiplexed readout and accompanying room-temperature electronics. Microwave-frequency resonators are a popular tool for cryogenic multiplexing, with the potential to multiplex thousands of detector channels on one readout line. The SMuRF system provides the capability for reading out up to 3328 channels across a 4–8 GHz bandwidth. Notably, the SMuRF system is unique in its implementation of a closed-loop tone-tracking algorithm that minimizes RF power transmitted to the cold amplifier, substantially relaxing system linearity requirements and effective noise from intermodulation products. Here, we present a description of the hardware, firmware, and software systems of the SMuRF electronics, comparing achieved performance with science-driven design requirements. In particular, we focus on the case of large-channel-count, low-bandwidth applications, but the system has been easily reconfigured for high-bandwidth applications. The system described here has been successfully deployed in lab settings and field sites around the world and is baselined for use on upcoming large-scale observatories.

     
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  3. Abstract

    The physiological asymmetry between daughters of a mother bacterium is produced by the inheritance of either old poles, carrying non-genetic damage, or newly synthesized poles. However, as bacteria display long-term growth stability leading to physiological immortality, there is controversy on whether asymmetry corresponds to aging. Here we show that deterministic age structure landscapes emerge from physiologically immortal bacterial lineages. Through single-cell microscopy and microfluidic techniques, we demonstrate that aging and rejuvenating bacterial lineages reach two distinct states of growth equilibria. These equilibria display stabilizing properties, which we quantified according to the compensatory trajectories of continuous lineages throughout generations. Finally, we show that the physiological asymmetry between aging and rejuvenating lineages produces complex age structure landscapes, resulting in a deterministic phenotypic heterogeneity that is neither an artifact of starvation nor a product of extrinsic damage. These findings indicate that physiological immortality and cellular aging can both be manifested in single celled organisms.

     
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  4. Zmuidzinas, Jonas ; Gao, Jian-Rong (Ed.)
    Observations of the Cosmic Microwave Background rely on cryogenic instrumentation with cold detectors, readout, and optics providing the low noise performance and instrumental stability required to make more sensitive measurements. It is therefore critical to optimize all aspects of the cryogenic design to achieve the necessary performance, with low temperature components and acceptable system cooling requirements. In particular, we will focus on our use of thermal filters and cold optics, which reduce the thermal load passed along to the cryogenic stages. To test their performance, we have made a series of in situ measurements while integrating the third receiver for the BICEP Array telescope. In addition to characterizing the behavior of this receiver, these measurements continue to refine the models that are being used to inform design choices being made for future instruments. 
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  5. Zmuidzinas, Jonas ; Gao, Jian-Rong (Ed.)
    The BICEP3 Polarimeter is a small aperture, refracting telescope, dedicated to the observation of the Cosmic Microwave Background (CMB) at 95GHz. It is designed to target degree angular scale polarization patterns, in particular the very-much-sought-after primordial B-mode signal, which is a unique signature of cosmic inflation. The polarized signal from the sky is reconstructed by differencing co-localized, orthogonally polarized superconducting Transition Edge Sensor (TES) bolometers. In this work, we present absolute measurements of the polarization response of the detectors for more than approximately 800 functioning detector pairs of the BICEP3 experiment, out of a total of approximately 1000. We use a specifically designed Rotating Polarized Source (RPS) to measure the polarization response at multiple source and telescope boresight rotation angles, to fully map the response over 360 degrees. We present here polarization properties extracted from on-site calibration data taken in January 2022. A similar calibration campaign was performed in 2018, but we found that our constraint was dominated by systematics on the level of approximately 0.5° . After a number of improvements to the calibration set-up, we are now able to report a significantly lower level of systematic contamination. In the future, such precise measurements will be used to constrain physics beyond the standard cosmological model, namely cosmic birefringence. 
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  6. Abstract

    Reproductive isolation is often achieved when genes that are neutral or beneficial in their genomic background become functionally incompatible in a foreign genomic background, causing inviability, sterility or other forms of low fitness in hybrids. Recent studies suggest that mitonuclear interactions are among the initial incompatibilities to evolve at early stages of population divergence across taxa. Yet, the genomic architecture of mitonuclear incompatibilities has rarely been elucidated. We employ an experimental evolution approach starting with low‐fitness F2interpopulation hybrids of the copepodTigriopus californicus, in which frequencies of compatible and incompatible nuclear alleles change in response to an alternative mitochondrial background. After about nine generations, we observe a generalized increase in population size and in survivorship, suggesting efficiency of selection against maladaptive phenotypes. Whole genome sequencing of evolved populations showed some consistent allele frequency changes across three replicates of each reciprocal cross, but markedly different patterns between mitochondrial backgrounds. In only a few regions (~6.5% of the genome), the same parental allele was overrepresented irrespective of the mitochondrial background. About 33% of the genome showed allele frequency changes consistent with divergent selection, with the location of these genomic regions strongly differing between mitochondrial backgrounds. In 87% and 89% of these genomic regions, the dominant nuclear allele matched the associated mitochondrial background, consistent with mitonuclear co‐adaptation. These results suggest that mitonuclear incompatibilities have a complex polygenic architecture that differs between populations, potentially generating genome‐wide barriers to gene flow between closely related taxa.

     
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  7. The BICEP/Keck series of experiments target the Cosmic Microwave Background at degree-scale resolution from the South Pole. Over the next few years, the "Stage-3" BICEP Array (BA) telescope will improve the program's frequency coverage and sensitivity to primordial B-mode polarization by an order of magnitude. The first receiver in the array, BA1, began observing at 30/40 GHz in early 2020. The next two receivers, BA2 and BA3, are currently being assembled and will map the southern sky at frequencies ranging from 95 GHz to 150 GHz. Common to all BA receivers is a refractive, on-axis, cryogenic optical design that focuses microwave radiation onto a focal plane populated with antenna-coupled bolometers. High-performance antireflective coatings up to 760 mm in aperture are needed for each element in the optical chain, and must withstand repeated thermal cycles down to 4 K. Here we present the design and fabrication of the 30/40 GHz anti-reflection coatings for the recently deployed BA1 receiver, then discuss laboratory measurements of their reflectance. We review the lamination method for these single- and dual-layer plastic coatings with indices matched to various polyethylene, nylon and alumina optics. We also describe ongoing efforts to optimize coatings for the next BA cryostats, which may inform technological choices for future Small-Aperture Telescopes of the CMB "Stage 4" experiment. 
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  8. Zmuidzinas, Jonas ; Gao, Jian-Rong (Ed.)
  9. Zmuidzinas, Jonas ; Gao, Jian-Rong (Ed.)