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Microtubule-kinesin active fluids are distinguished from conventional passive fluids by their unique ability to consume local fuel, ATP, to generate internal active stress. This stress drives internal flow autonomously and promotes micromixing, without the need for external pumps. When confined within a looped boundary, these active fluids can spontaneously self-organize into river-like flows. However, the influence of a moving boundary on these flow behaviors has remained elusive. Here, we investigate the role of a moving boundary on the flow kinematics of active fluids. We confined the active fluid within a thin cuboidal boundary with one side serving as a mobile boundary. Our data reveals that when the boundary's moving speed does not exceed the intrinsic flow speed of the active fluid, the fluid is dominated by chaotic, turbulence-like flows. The velocity correlation length of the flow is close to the intrinsic vortex size induced by the internal active stress. Conversely, as the boundary's moving speed greatly exceeds that of the active fluid, the flow gradually transitions to a conventional cavity flow pattern. In this regime, the velocity correlation length increases and saturates to those of water. Our work elucidates the intricate interplay between a moving boundary and active fluid behavior. *We acknowledge support from the National Science Foundation (NSF-CBET-2045621). 

Today's robotic laboratories for drones are housed in a large room. At times, they are the size of a warehouse. These spaces are typically equipped with permanent devices to localize the drones, e.g., Vicon Infrared cameras. Significant time is invested to fine-tune the localization apparatus to compute and control the position of the drones. One may use these laboratories to develop a 3D multimedia system with miniature sized drones configured with light sources. As an alternative, this brave new idea paper envisions shrinking these room-sized laboratories to the size of a cube or cuboid that sits on a desk and costs less than 10K dollars. The resulting Dronevision (DV) will be the size of a 1990s Television. In addition to light sources, its Flying Light Specks (FLSs) will be network-enabled drones with storage and processing capability to implement decentralized algorithms. The DV will include a localization technique to expedite development of 3D displays. It will act as a haptic interface for a user to interact with and manipulate the 3D virtual illuminations. It will empower an experimenter to design, implement, test, debug, and maintain software and hardware that realize novel algorithms in the comfort of their office without having to reserve a laboratory. In addition to enhancing productivity, it will improve safety of the experimenter by minimizing the likelihood of accidents. This paper introduces the concept of a DV, the research agenda one may pursue using this device, and our plans to realize one. 

In this paper, we introduce an innovative approach to multi-human robot interaction, leveraging the capabilities of omnicopters. These agile aerial vehicles are poised to revolutionize haptic feedback by offering complex sensations with 6 degrees of freedom (6DoF) movements. Unlike traditional systems, our envisioned method enables haptic rendering without the need for tilt, offering a more intuitive and seamless interaction experience. Furthermore, we propose using omnicopter swarms in human-robot interaction, these omnicopters can collaboratively emulate and render intricate objects in real-time. This swarm-based rendering not only expands the realm of tangible human-robot interactions but also holds potential in diverse applications, from immersive virtual environments to tactile guidance in physical tasks. Our vision outlines a future where robots and humans interact in more tangible and sophisticated ways, pushing the boundaries of current haptic technology. 

We propose a novel Learned Alternating Minimization Algorithm (LAMA) for dual-domain sparse-view CT image reconstruction. LAMA is naturally induced by a variational model for CT reconstruction with learnable nonsmooth nonconvex regularizers, which are parameterized as composite functions of deep networks in both image and sinogram domains. To minimize the objective of the model, we incorporate the smoothing technique and residual learning architecture into the design of LAMA. We show that LAMA substantially reduces network complexity, improves memory efficiency and reconstruction accuracy, and is provably convergent for reliable reconstructions. Extensive numerical experiments demonstrate that LAMA outperforms existing methods by a wide margin on multiple benchmark CT datasets. 

In this work, we investigate the impact of class imbalance on the accuracy and diversity of synthetic samples generated by conditional generative adversarial networks (CGAN) models. Though many studies utilizing GANs have seen extraordinary success in producing realistic image samples, these studies generally assume the use of well-processed and balanced benchmark image datasets, including MNIST and CIFAR-10. However, well-balanced data is uncommon in real world applications such as detecting fraud, diagnosing diabetes, and predicting solar flares. It is well known that when class labels are not distributed uniformly, the predictive ability of classification algorithms suffers significantly, a phenomenon known as the "class-imbalance problem." We show that the imbalance in the training set can also impact sample generation of CGAN models. We utilize the well known MNIST datasets, controlling the imbalance ratio of certain classes within the data through sampling. We are able to show that both the quality and diversity of generated samples suffer in the presence of class imbalances and propose a novel framework named Two-stage CGAN to produce high-quality synthetic samples in such cases. Our results indicate that the proposed framework provides a significant improvement over typical oversampling and undersampling techniques utilized for class imbalance remediation. 

Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In particular, the long scanning time required and high radiation exposure associated with PET scans make obtaining these labels impractical. In this paper, we propose a dual-domain unsupervised PET image reconstruction method based on learned descent algorithm, which reconstructs high-quality PET images from sinograms without the need for image labels. Specifically, we unroll the proximal gradient method with a learnable norm for PET image reconstruction problem. The training is unsupervised, using measurement domain loss based on deep image prior as well as image domain loss based on rotation equivariance property. The experimental results demonstrate the superior performance of proposed method compared with maximum-likelihood expectation-maximization (MLEM), total-variation regularized EM (EM-TV) and deep image prior based method (DIP). 

Objective. Dynamic positron emission tomography (PET) imaging, which can provide information on dynamic changes in physiological metabolism, is now widely used in clinical diagnosis and cancer treatment. However, the reconstruction from dynamic data is extremely challenging due to the limited counts received in individual frame, especially in ultra short frames. Recently, the unrolled modelbased deep learning methods have shown inspiring results for low-count PET image reconstruction with good interpretability. Nevertheless, the existing model-based deep learning methods mainly focus on the spatial correlations while ignore the temporal domain. Approach. In this paper, inspired by the learned primal dual (LPD) algorithm, we propose the spatio-temporal primal dual network (STPDnet) for dynamic low-count PET image reconstruction. Both spatial and temporal correlations are encoded by 3D convolution operators. The physical projection of PET is embedded in the iterative learning process of the network, which provides the physical constraints and enhances interpretability. Main results. The experiments of both simulation data and real rat scan data have shown that the proposed method can achieve substantial noise reduction in both temporal and spatial domains and outperform the maximum likelihood expectation maximization, spatio-temporal kernel method, LPD and FBPnet. Significance. Experimental results show STPDnet better reconstruction performance in the low count situation, which makes the proposed method particularly suitable in whole-body dynamic imaging and parametric PET imaging that require extreme short frames and usually suffer from high level of noise.