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We presentGIGANTES, the most extensive and realistic void catalog suite ever released—containing over 1 billion cosmic voids covering a volume larger than the observable universe, more than 20 TB of data, and created by running the void finderVIDEonQUIJOTE’s halo simulations. TheGIGANTESsuite, spanning thousands of cosmological models, opens up the study of voids, answering compelling questions: Do voids carry unique cosmological information? How is this information correlated with galaxy information? Leveraging the large number of voids in theGIGANTESsuite, our Fisher constraints demonstrate voids contain additional information, critically tightening constraints on cosmological parameters. We use traditional void summary statistics (void size function, void density profile) and the void autocorrelation function, which independently yields an error of 0.13 eV on ∑m_νfor a 1h⁻³Gpc³simulation, without cosmic microwave background priors. Combining halos and voids we forecast an error of 0.09 eV from the same volume, representing a gain of 60% compared to halos alone. Extrapolating to next generation multi-Gpc³surveys such as the Dark Energy Spectroscopic Instrument, Euclid, the Spectro-Photometer for the History of the Universe and Ices Explorer, and the Roman Space Telescope, we expect voids should yield an independent determination of neutrino mass. Crucially,GIGANTESis the first void catalog suite expressly built for intensive machine-learning exploration. We illustrate this by training a neural network to perform likelihood-free inference on the void size function, giving a ∼20% constraint on Ω_m. Cosmology problems provide an impetus to develop novel deep-learning techniques. WithGIGANTES, machine learning gains an impressive data set, offering unique problems that will stimulate new techniques.