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Abstract NONEXPRESSER OF PATHOGENESIS-RELATED GENES 1 (NPR1) is the master regulator of salicylic acid-mediated basal and systemic acquired resistance in plants. Here, we report that NPR1 plays a pivotal role in restricting compatible infection by turnip mosaic virus, a member of the largest plant RNA virus genus Potyvirus , and that such resistance is counteracted by NUCLEAR INCLUSION B (NIb), the viral RNA-dependent RNA polymerase. We demonstrate that NIb binds to the SUMO-interacting motif 3 (SIM3) of NPR1 to prevent SUMO3 interaction and sumoylation, while sumoylation of NIb by SUMO3 is not essential but can intensify the NIb–NPR1 interaction. We discover that the interaction also impedes the phosphorylation of NPR1 at Ser11/Ser15. Moreover, we show that targeting NPR1 SIM3 is a conserved ability of NIb from diverse potyviruses. These data reveal a molecular “arms race” by which potyviruses deploy NIb to suppress NPR1-mediated resistance through disrupting NPR1 sumoylation. 

Acoustic resonances in open systems, which are usually associated with resonant modes characterized by complex eigenfrequencies, play a fundamental role in manipulating acoustic wave radiation and propagation. Notably, they are accompanied by considerable field enhancement, boosting interactions between waves and matter, and leading to various exciting applications. In the past two decades, acoustic metamaterials have enabled a high degree of control over tailoring acoustic resonances over a range of frequencies. Here, we provide an overview of recent advances in the area of acoustic resonances in non-Hermitian open systems, including Helmholtz resonators, metamaterials and metasurfaces, and discuss their applications in various acoustic devices, including sound absorbers, acoustic sources, vortex beam generation and imaging. We also discuss bound states in the continuum and their applications in boosting acoustic wave–matter interactions, active phononics and non-Hermitian acoustic resonances, including phononic topological insulators and the acoustic skin effect. 

All van der Waals Fe 3 GeTe 2 /Cr 2 Ge 2 Te 6 /graphite magnetic heterojunctions have been fabricated via mechanical exfoliation and stacking, and their magnetotransport properties are studied in detail. At low bias voltages, large negative junction magnetoresistances have been observed and are attributed to spin-conserving tunneling transport across an insulating Cr 2 Ge 2 Te 6 layer. With increasing bias, a crossover to Fowler–Nordheim tunneling takes place. The negative sign of the tunneling magnetoresistance suggests that the bottom of a conduction band in Cr 2 Ge 2 Te 6 belongs to minority spins, opposite to the findings of some first-principles calculations. This work shows that the vdW heterostructures based on 2D magnetic insulators are a valuable platform to gain further insight into spin polarized tunneling transport, which is the basis for pursuing high performance spintronic devices and a large variety of quantum phenomena. 

We consider the problem of synthesizing good-enough (GE)-strategies for linear temporal logic (LTL) over finite traces or LTLf for short.The problem of synthesizing GE-strategies for an LTL formula φ over infinite traces reduces to the problem of synthesizing winning strategies for the formula (∃Oφ)⇒φ where O is the set of propositions controlled by the system.We first prove that this reduction does not work for LTLf formulas.Then we show how to synthesize GE-strategies for LTLf formulas via the Good-Enough (GE)-synthesis of LTL formulas.Unfortunately, this requires to construct deterministic parity automata on infinite words, which is computationally expensive.We then show how to synthesize GE-strategies for LTLf formulas by a reduction to solving games played on deterministic Büchi automata, based on an easier construction of deterministic automata on finite words.We show empirically that our specialized synthesis algorithm for GE-strategies outperforms the algorithms going through GE-synthesis of LTL formulas by orders of magnitude.