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We conducted a 2x2 Wizard of Oz between-subject user study with sixteen healthy older adults. We investigated how to make social robots converse more naturally and reciprocally through unstructured conversation. We varied the level of interaction by changing the level of verbal and nonverbal communication the robot provided. Participants interacted with the robot for eight sessions engaging in an unstructured conversation. These conversations lasted thirty minutes to an hour. This paper will evaluate four questions from the post-interaction survey individuals completed after each session with the robot. The questions include: (i) I had fun talking to the robot; (ii) I felt I had a meaningful conversation; (iii) I was engaged the whole interaction; and (iv) I would consider the robot my friend. All participants reported they were engaged, had a meaningful conversation, and had fun during all eight sessions. Seven individuals felt the robot was their friend. 

COVID-19 is exacerbating isolation issues faced by older adults, which may lead to increased risk for depression and other mental health issues. Social robots are being explored for their potential to alleviate these challenges through conversational therapy, companionship, and connectedness regardless of where older adults chose to age in place—from home to long-term care facilities. This is a discussion piece with the objective of raising awareness to the topic of social isolation within older adults and current limitations in the field of social robotics. We discuss the state of the art in social robotics for aging in place and bring attention to remaining challenges for addressing isolation and mental health especially during and after COVID-19. This paper provides a discussion on critical differences between environments where older individuals age, and how designs should account for these variations. Lastly, this paper highlights the physical and mental health issues of caregivers and provides a discussion of challenges that remain toward using social robotics to assist those who take care of the aging population. 

As a 3D bioprinting technique, hydrogel stereolithography has historically been limited in its ability to capture the spatial heterogeneity that permeates mammalian tissues and dictates structure–function relationships. This limitation stems directly from the difficulty of preventing unwanted material mixing when switching between different liquid bioinks. Accordingly, we present the development, characterization, and application of a multi-material stereolithography bioprinter that provides controlled material selection, yields precise regional feature alignment, and minimizes bioink mixing. Fluorescent tracers were first used to highlight the broad design freedoms afforded by this fabrication strategy, complemented by morphometric image analysis to validate architectural fidelity. To evaluate the bioactivity of printed gels, 344SQ lung adenocarcinoma cells were printed in a 3D core/shell architecture. These cells exhibited native phenotypic behavior as evidenced by apparent proliferation and formation of spherical multicellular aggregates. Cells were also printed as pre-formed multicellular aggregates, which appropriately developed invasive protrusions in response to hTGF-β1. Finally, we constructed a simplified model of intratumoral heterogeneity with two separate sub-populations of 344SQ cells, which together grew over 14 days to form a dense regional interface. Together, these studies highlight the potential of multi-material stereolithography to probe heterotypic interactions between distinct cell types in tissue-specific microenvironments.

 

This paper highlights current technological limitations and offers recommendations for scientists and engineers when designing devices to support aging in place. Existing technology for older adults to support independent living is examined as well as the implications of contextual factors, namely, location, on how people live and age based on the location in which they reside. This is the first review to investigate how challenges of aging change relative to location of residence and, subsequently, how such variation may inform technological solutions. To date, few devices consider the environment in which older individuals age. Places examined include aging: at home; assisted living facilities; nursing homes; and family housing. Challenges found in common across these locations were financial strain and isolation. In addition, each setting was found to have its own unique hurdles. Understanding these barriers is essential to developing technology that enables older adults to successfully age in place. 

Solid organs transport fluids through distinct vascular networks that are biophysically and biochemically entangled, creating complex three-dimensional (3D) transport regimes that have remained difficult to produce and study. We establish intravascular and multivascular design freedoms with photopolymerizable hydrogels by using food dye additives as biocompatible yet potent photoabsorbers for projection stereolithography. We demonstrate monolithic transparent hydrogels, produced in minutes, comprising efficient intravascular 3D fluid mixers and functional bicuspid valves. We further elaborate entangled vascular networks from space-filling mathematical topologies and explore the oxygenation and flow of human red blood cells during tidal ventilation and distension of a proximate airway. In addition, we deploy structured biodegradable hydrogel carriers in a rodent model of chronic liver injury to highlight the potential translational utility of this materials innovation.