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Somatic mosaicism is defined as an occurrence of two or more populations of cells having genomic sequences differing at given loci in an individual who is derived from a single zygote. It is a characteristic of multicellular organisms that plays a crucial role in normal development and disease. To study the nature and extent of somatic mosaicism in autism spectrum disorder, bipolar disorder, focal cortical dysplasia, schizophrenia, and Tourette syndrome, a multi-institutional consortium called the Brain Somatic Mosaicism Network (BSMN) was formed through the National Institute of Mental Health (NIMH). In addition to genomic data of affected and neurotypical brains, the BSMN also developed and validated a best practices somatic single nucleotide variant calling workflow through the analysis of reference brain tissue. These resources, which include >400 terabytes of data from 1087 subjects, are now available to the research community via the NIMH Data Archive (NDA) and are described here.

 

he pervasive operation of customer drones, or small-scale unmanned aerial vehicles (UAVs), has raised serious concerns about their privacy threats to the public. In recent years, privacy invasion events caused by customer drones have been frequently reported. Given such a fact, timely detection of invading drones has become an emerging task. Existing solutions using active radar, video or acoustic sensors are usually too costly (especially for individuals) or exhibit various constraints (e.g., requiring visual line of sight). Recent research on drone detection with passive RF signals provides an opportunity for low-cost deployment of drone detectors on commodity wireless devices. However, the state of the arts in this direction rely on line-of-sight (LOS) RF signals, which makes them only work under very constrained conditions. The support of more common scenarios, i.e., non-line-of-sight (NLOS), is still missing for low-cost solutions. In this paper, we propose a novel detection system for privacy invasion caused by customer drone. Our system is featured with accurate NLOS detection with low-cost hardware (under $50). By exploring and validating the relationship between drone motions and RF signal under the NLOS condition, we find that RF signatures of drones are somewhat “amplified” by multipaths in NLOS. Based on this observation, we design a two-step solution which first classifies received RSS measurements into LOS and NLOS categories; deep learning is then used to extract the signatures and ultimately detect the drones. Our experimental results show that LOS and NLOS signals can be identified at accuracy rates of 98.4% and 96% respectively. Our drone detection rate for NLOS condition is above 97% with a system implemented using Raspberry PI 3 B+.