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  1. Abstract

    Flexure occurs on intermediate geologic timescales (∼1 Myr) due to volcanic‐island building at the Island of Hawaii, and the deformational response of the lithosphere is simultaneously elastic, plastic, and ductile. At shallow depths and low temperatures, elastic deformation transitions to frictional failure on faults where stresses exceed a threshold value, and this complex rheology controls the rate of deformation manifested by earthquakes. In this study, we estimate the seismic strain rate based on earthquakes recorded between 1960 and 2019 at Hawaii, and the estimated strain rate with 10−18–10−15s−1in magnitude exhibits a local minimum or neutral bending plane at 15 km depth within the lithosphere. In comparison, flexure and internal deformation of the lithosphere are modeled in 3D viscoelastic loading models where deformation at shallow depths is accommodated by frictional sliding on faults and limited by the frictional coefficient (μf), and at larger depths by low‐temperature plasticity and high‐temperature creep. Observations of flexure and the seismic strain rate are best‐reproduced by models withμf = 0.3 ± 0.1 and modified laboratory‐derived low‐temperature plasticity. Results also suggest strong lateral variations in the frictional strength of faults beneath Hawaii. Our models predict a radial pattern of compressive stress axes relative to central Hawaii consistent with observations of earthquake pressure (P) axes. We demonstrate that the dip angle of this radial axis is essential to discerning a change in the curvature of flexure, and therefore has implications for constraining lateral variations in lithospheric strength.

     
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  3. Abstract

    Previous studies have suggested that disorders of consciousness (DOC) after severe brain injury may result from disconnections of the thalamo‐cortical system. However, thalamo‐cortical connectivity differences between vegetative state (VS), minimally conscious state minus (MCS−, i.e., low‐level behavior such as visual pursuit), and minimally conscious state plus (MCS+, i.e., high‐level behavior such as language processing) remain unclear. Probabilistic tractography in a sample of 25 DOC patients was employed to assess whether structural connectivity in various thalamo‐cortical circuits could differentiate between VS, MCS−, and MCS+ patients. First, the thalamus was individually segmented into seven clusters based on patterns of cortical connectivity and tested for univariate differences across groups. Second, reconstructed whole‐brain thalamic tracks were used as features in a multivariate searchlight analysis to identify regions along the tracks that were most informative in distinguishing among groups. At the univariate level, it was found that VS patients displayed reduced connectivity in most thalamo‐cortical circuits of interest, including frontal, temporal, and sensorimotor connections, as compared with MCS+, but showed more pulvinar‐occipital connections when compared with MCS−. Moreover, MCS− exhibited significantly less thalamo‐premotor and thalamo‐temporal connectivity than MCS+. At the multivariate level, it was found that thalamic tracks reaching frontal, parietal, and sensorimotor regions, could discriminate, up to 100% accuracy, across each pairwise group comparison. Together, these findings highlight the role of thalamo‐cortical connections in patients' behavioral profile and level of consciousness. Diffusion tensor imaging combined with machine learning algorithms could thus potentially facilitate diagnostic distinctions in DOC and shed light on the neural correlates of consciousness.Hum Brain Mapp 38:431–443, 2017. ©2016 Wiley Periodicals, Inc.

     
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