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Cellular considerations for optimizing bone cell culture and remodeling in a lab-on-a-chip platform

https://doi.org/10.2144/btn-2019-0115

Truesdell, Sharon L ; George, Estee L ; Saunders, Marnie M ( May 2020 , BioTechniques)

Method summary Methods of culturing bone cells out to 7 weeks within a lab-on-a-chip platform have been optimized and allow for quantification of bone remodeling functional activity (formation/resorption) and soluble effects of mechanical loading.
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A Lab-On-A-Chip Platform for Stimulating Osteocyte Mechanotransduction and Analyzing Functional Outcomes of Bone Remodeling

https://doi.org/10.3791/61076

Truesdell, Sharon L. ; George, Estee L. ; Van Vranken, Christopher C. ; Saunders, Marnie M. ( January 2020 , Journal of Visualized Experiments)

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Bone remodeling platforms: Understanding the need for multicellular lab-on-a-chip systems and predictive agent-based models

https://doi.org/10.3934/mbe.2020063

L. Truesdell, Sharon ; M. Saunders, Marnie ( January 2020 , Mathematical Biosciences and Engineering)

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Current Trends in Osteoporosis Diagnostics: An Opportunity for Quantitative Ultrasound and Biomarkers

https://doi.org/10.26717/BJSTR.2019.23.003838

Saunders, Marnie M ( November 2019 , Biomedical Journal of Scientific & Technical Research)

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The effects of mechanically loaded osteocytes and inflammation on bone remodeling in a bisphosphonate-induced environment

https://doi.org/10.1016/j.bone.2019.07.008

George, Estee L. ; Truesdell, Sharon L. ; Magyar, Alexandria L. ; Saunders, Marnie M. ( October 2019 , Bone)

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3D Printed Loading Device for Inducing Cellular Mechanotransduction via Matrix Deformation

https://doi.org/10.1007/s11340-019-00531-1

Truesdell, S. L. ; George, E. L. ; Seno, C. E. ; Saunders, M. M. ( October 2019 , Experimental Mechanics)

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Lab-on-a-chip platforms for quantification of multicellular interactions in bone remodeling

https://doi.org/10.1016/j.yexcr.2018.02.027

George, Estee L. ; Truesdell, Sharon L. ; York, Spencer L. ; Saunders, Marnie M. ( April 2018 , Experimental Cell Research)

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