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Non-Native Peptides Capable of Pan-Activating the agr Quorum Sensing System across Multiple Specificity Groups of Staphylococcus epidermidis

https://doi.org/10.1021/acschembio.1c00240

West, Korbin H. ; Shen, Wenqi ; Eisenbraun, Emma L. ; Yang, Tian ; Vasquez, Joseph K. ; Horswill, Alexander R. ; Blackwell, Helen E. ( June 2021 , ACS Chemical Biology)
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Conformational Switch to a β-Turn in a Staphylococcal Quorum Sensing Signal Peptide Causes a Dramatic Increase in Potency

https://doi.org/10.1021/jacs.9b05513

Vasquez, Joseph K. ; West, Korbin H. ; Yang, Tian ; Polaske, Thomas J. ; Cornilescu, Gabriel ; Tonelli, Marco ; Blackwell, Helen E. ( December 2019 , Journal of the American Chemical Society)

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Simplified Autoinducing Peptide Mimetics with Single-Nanomolar Activity Against the Staphylococcus aureus AgrC Quorum Sensing Receptor

https://doi.org/10.1021/acsinfecdis.9b00002

Vasquez, Joseph K. ; Blackwell, Helen E. ( February 2019 , ACS Infectious Diseases)
Selection of Appropriate Autoinducer Analogues for the Modulation of Quorum Sensing at the Host–Bacterium Interface

https://doi.org/10.1021/acschembio.8b00676

Palmer, Andrew G. ; Senechal, Amanda C. ; Haire, Timothy C. ; Mehta, Nidhi P. ; Valiquette, Sara D. ; Blackwell, Helen E. ( November 2018 , ACS Chemical Biology)

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The State of the Union Is Strong: a Review of ASM's 6th Conference on Cell-Cell Communication in Bacteria

https://doi.org/10.1128/JB.00291-18

Brown, Sam P. ; Blackwell, Helen E. ; Hammer, Brian K. ; O'Toole, George ( July 2018 , Journal of Bacteriology)

ABSTRACT The 6th American Society for Microbiology Conference on Cell-Cell Communication in Bacteria convened from 16 to 19 October 2017 in Athens, GA. In this minireview, we highlight some of the research presented at that meeting that addresses central questions emerging in the field, including the following questions. How are cell-cell communication circuits designed to generate responses? Where are bacteria communicating? Finally, why are bacteria engaging in such behaviors?
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