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Abstract Changes in climate are expected to influence discharge of the lower Mississippi River, but projections disagree on whether discharge will increase or decrease over the coming century. Using a reconstructed median peak annual flow for the past 1,500 years based on geomorphic scaling laws, we show that discharge on the lower Mississippi River decreased during the Medieval era (c. 1000–1200 CE)—a period of regionally warm and dry conditions that serves as a partial analog for projected warming. These changes in discharge inferred from channel morphology track discharge simulated in the Community Earth System Model Last Millennium Ensemble. Simulations show that decreased Medieval era discharge is driven primarily by regionally enhanced evapotranspiration. Our findings are consistent with 21st century projections of decreased discharge on the lower Mississippi River under moderate greenhouse forcing scenarios, and demonstrate consistency between reconstructed and simulated discharge over the last millennium. 

Abstract Floods and droughts in the Mississippi River basin are perennial hazards that cause severe economic disruption. Here we develop and analyze a new lipid biomarker record from Horseshoe Lake (Illinois, USA) to evaluate the climatic conditions associated with hydroclimatic extremes that occurred in this region over the last 1,800 years. We present geochemical proxy evidence of temperature and moisture variability using branched glycerol dialkyl glycerol tetraethers (brGDGTs) and plant leaf wax hydrogen isotopic composition (δ²H_wax) and use isotope‐enabled coupled model simulations to diagnose the controls on these proxies. Our data show pronounced warming during the Medieval era (CE 1000–1,600) that corresponds to midcontinental megadroughts. Severe floods on the upper Mississippi River basin also occurred during the Medieval era and correspond to periods of enhanced warm‐season moisture. Our findings imply that projected increases in temperature and warm‐season precipitation could enhance both drought and flood hazards in this economically vital region.