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Conference Proceedings from the 2018 NSF Funded Crosscutting Concept Summit. Includes chapters : 1. The Need for a Summit for Examining the Potential for Crosscutting Concepts to Support Three-Dimensional Science Learning - Sarah J. Fick, Jeffrey Nordine, & Kevin W. McElhaney 2. CCC Summit Agenda - Summit Organizing Committee 3. CCC Summit Attendees 4. Supporting Students’ Learning of Science Content and Practices Through the Intentional Incorporation and Scaffolding of Crosscutting Concept - Sarah J. Fick, Lauren Barth-Cohen, Ann Rivet, Melanie Cooper, Jason Buell, & Aneesha Badrinarayan 5. Using the Crosscutting Concepts to Integrate Science and Engineering - Kevin W. McElhaney, Christine Cunningham, Kristin Mayer, Joi Merritt, Nancy Ruzycki, & Cary Sneider 6. The Integration of Cross-Cutting Concepts in Three-Dimensional Learning - Susan Yoon, Cesar Delgado, TJ McKenna, Joe Krajcik, Lauren Levites, & Art Sussman 7. CCCs as epistemic heuristics to guide student sense-making of phenomena - Charles W. Anderson, Brian Gane, Cindy E. Hmelo-Silver, Lindsey Mohan, & Tina Vo 8. Modeling the Role of Crosscutting Concepts for Strengthening Science Learning of All Students - Abeera P. Rehmat, Okhee Lee, Jeffrey Nordine, Ann M. Novak, Johnathan Osborne, & Ted Willard 9. Looking Forward: Setting an Agenda for Research into the Crosscutting Concepts - Jeffrey Nordine, Lauren Barth-Cohen, Brian Gane, TJ McKenna, & Tina Vo