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Oguz, Ipek; Noble, Jack; Li, Xiaoxiao; Styner, Martin; Baumgartner, Christian; Rusu, Mirabela; Heinmann, Tobias; Kontos, Despina; Landman, Bennett; Dawant, Benoit (Ed.)Many applications in machine vision and medical imaging require the capture of images from a scene with very low radiance, which may result in very noisy images and videos. An important example of such an application is the imaging of fluorescently-labeled tissue in fluorescence-guided surgery. Medical imaging systems, especially when intended to be used in surgery, are designed to operate in well-lit environments and use optical filters, time division, or other strategies that allow the simultaneous capture of low radiance fluorescence video and a well-lit visible light video of the scene. This work demonstrates video denoising can be dramatically improved by utilizing deep learning together with motion and textural cues from the noise-free video.more » « less
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