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  1. Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial intelligence. Organoids, three-dimensional miniature organ-like structures cultivated from stem cells, offer an unparalleled opportunity to simulate complex human organ systems in vitro. Through the convergence of organoid technology and AI, researchers gain the means to accelerate discoveries and insights across various disciplines. Artificial intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors, intricate cellular interactions, and dynamic responses to stimuli. This synergy empowers the development of predictive models, precise disease simulations, and personalized medicine approaches, revolutionizing our understanding of human development, disease mechanisms, and therapeutic interventions. Organoid Intelligence holds the promise of reshaping how we perceive in vitro modeling, propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development. 
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    Free, publicly-accessible full text available March 1, 2025
  2. Abstract

    Artificial intelligence (AI) is shifting the paradigm of two-phase heat transfer research. Recent innovations in AI and machine learning uniquely offer the potential for collecting new types of physically meaningful features that have not been addressed in the past, for making their insights available to other domains, and for solving for physical quantities based on first principles for phase-change thermofluidic systems. This review outlines core ideas of current AI technologies connected to thermal energy science to illustrate how they can be used to push the limit of our knowledge boundaries about boiling and condensation phenomena. AI technologies for meta-analysis, data extraction, and data stream analysis are described with their potential challenges, opportunities, and alternative approaches. Finally, we offer outlooks and perspectives regarding physics-centered machine learning, sustainable cyberinfrastructures, and multidisciplinary efforts that will help foster the growing trend of AI for phase-change heat and mass transfer.

     
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  3. As a global technoscientific form involving various forces and stakeholders, research and development (R&D) in artificial intelligence (AI) transcends corporate, national and institutional boundaries. Incorporating transnational rhetorical analysis and corpus-assisted discourse analysis, this article examines the global cultural flows surrounding AI constructed in official and media discourses in the US and China. We propose a new theoretical concept of knowledgescape that expands the toolkits of global flows and provides new explanatory power about global innovation and competition. This concept sheds light on the global processes, mechanisms and power dynamics of the production, dissemination, consumption and contestation of cutting-edge knowledge.

     
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  4. Abstract

    Metal-organic frameworks (MOFs) exhibit great promise for CO2capture. However, finding the best performing materials poses computational and experimental grand challenges in view of the vast chemical space of potential building blocks. Here, we introduce GHP-MOFassemble, a generative artificial intelligence (AI), high performance framework for the rational and accelerated design of MOFs with high CO2adsorption capacity and synthesizable linkers. GHP-MOFassemble generates novel linkers, assembled with one of three pre-selected metal nodes (Cu paddlewheel, Zn paddlewheel, Zn tetramer) into MOFs in a primitive cubic topology. GHP-MOFassemble screens and validates AI-generated MOFs for uniqueness, synthesizability, structural validity, uses molecular dynamics simulations to study their stability and chemical consistency, and crystal graph neural networks and Grand Canonical Monte Carlo simulations to quantify their CO2adsorption capacities. We present the top six AI-generated MOFs with CO2capacities greater than 2m mol g−1, i.e., higher than 96.9% of structures in the hypothetical MOF dataset.

     
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  5. Abstract

    Following our previous study of Artificial Intelligence Assisted Inversion (AIAI) of supernova analyses, we train a set of deep neural networks based on the 1D radiative transfer code TARDIS to simulate the optical spectra of Type Ia supernovae (SNe Ia) between 10 and 40 days after the explosion. The neural networks are applied to derive the mass of56Ni in velocity ranges above the photosphere for a sample of 124 well-observed SNe Ia in the TARDIS model context. A subset of the SNe have multi-epoch observations for which the decay of the radioactive56Ni can be used to test the AIAI quantitatively. The56Ni mass derived from AIAI using the observed spectra as inputs for this subset agrees with the radioactive decay rate of56Ni. AIAI reveals that a spectral signature near 3890 Å is related to the Niii4067Å line, and the56Ni mass deduced from AIAI is found to be correlated with the light-curve shapes of SNe Ia, with SNe Ia with broader light curves showing larger56Ni mass in the envelope above the photosphere. AIAI enables spectral data of SNe to be quantitatively analyzed under theoretical frameworks based on well-defined physical assumptions.

     
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  6. Artificial Intelligence (AI) and machine learning have advanced healthcare by defining relationships in complex conditions. Out-of-hospital cardiac arrest (OHCA) is a medically complex condition with several etiologies. Survival for OHCA has remained static at 10% for decades in the United States. Treatment of OHCA requires the coordination of numerous interventions, including the delivery of multiple medications. Current resuscitation algorithms follow a single strict pathway, regardless of fluctuating cardiac physiology. OHCA resuscitation requires a real-time biomarker that can guide interventions to improve outcomes. End tidal capnography (ETCO2) is commonly implemented by emergency medical services professionals in resuscitation and can serve as an ideal biomarker for resuscitation. However, there are no effective conceptual frameworks utilizing the continuous ETCO2 data. In this manuscript, we detail a conceptual framework using AI and machine learning techniques to leverage ETCO2 in guided resuscitation. 
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    Free, publicly-accessible full text available January 3, 2025
  7. Abstract

    Collective privacy loss becomes a colossal problem, an emergency for personal freedoms and democracy. But, are we prepared to handle personal data as scarce resource and collectively share data under the doctrine: as little as possible, as much as necessary? We hypothesize a significant privacy recovery if a population of individuals, the data collective, coordinates to share minimum data for running online services with the required quality. Here, we show how to automate and scale-up complex collective arrangements for privacy recovery using decentralized artificial intelligence. For this, we compare for the first time attitudinal, intrinsic, rewarded, and coordinated data sharing in a rigorous living-lab experiment of high realism involving >27,000 real data disclosures. Using causal inference and cluster analysis, we differentiate criteria predicting privacy and five key data-sharing behaviors. Strikingly, data-sharing coordination proves to be a win–win for all: remarkable privacy recovery for people with evident costs reduction for service providers.

     
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  8. Contribution: A novel proactive and collaborative learning paradigm was proposed to engage learners with different backgrounds and enable effective retention and transfer of the multidisciplinary artificial intelligence (AI)-cybersecurity knowledge. Specifically, the proposed learning paradigm contains: 1) an immersive learning environment to motivate the students for exploring AI/machine learning (ML) development in the context of real-world cybersecurity scenarios by constructing learning models with tangible objects and 2) a proactive education paradigm designed with the use of collaborative learning activities based on game-based learning and social constructivism. Background: Increasing evidence shows that AI techniques can be manipulated, evaded, and misled, which can result in new and profound security implications. There is an education and training gap to foster a qualified cyber-workforce that understands the usefulness, limitations, and best practices of AI technologies in the cybersecurity domain. Efforts have been made to incorporate a comprehensive curriculum to meet the demand. There still remain essential challenges for effectively educating students on the interaction of AI and cybersecurity. Intended Outcomes: A novel proactive and collaborative learning paradigm is proposed to educate and train a qualified cyber-workforce in this new era where security breaches, privacy violations, and AI have become commonplace. Application Design: The development of this learning paradigm is grounded in the pedagogical approaches of technology-mediated learning and social constructivism. Findings: Although the research work is still ongoing, the prototype learning paradigm has shown encouraging results in promoting the learners’ engagement in applied AI learning. 
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    Free, publicly-accessible full text available December 21, 2024
  9. Abstract Artificial intelligence (AI) is already widely used in daily communication, but despite concerns about AI’s negative effects on society the social consequences of using it to communicate remain largely unexplored. We investigate the social consequences of one of the most pervasive AI applications, algorithmic response suggestions (“smart replies”), which are used to send billions of messages each day. Two randomized experiments provide evidence that these types of algorithmic recommender systems change how people interact with and perceive one another in both pro-social and anti-social ways. We find that using algorithmic responses changes language and social relationships. More specifically, it increases communication speed, use of positive emotional language, and conversation partners evaluate each other as closer and more cooperative. However, consistent with common assumptions about the adverse effects of AI, people are evaluated more negatively if they are suspected to be using algorithmic responses. Thus, even though AI can increase the speed of communication and improve interpersonal perceptions, the prevailing anti-social connotations of AI undermine these potential benefits if used overtly. 
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    Free, publicly-accessible full text available December 1, 2024
  10. Abstract Neuroscience has long been an essential driver of progress in artificial intelligence (AI). We propose that to accelerate progress in AI, we must invest in fundamental research in NeuroAI. A core component of this is the embodied Turing test, which challenges AI animal models to interact with the sensorimotor world at skill levels akin to their living counterparts. The embodied Turing test shifts the focus from those capabilities like game playing and language that are especially well-developed or uniquely human to those capabilities – inherited from over 500 million years of evolution – that are shared with all animals. Building models that can pass the embodied Turing test will provide a roadmap for the next generation of AI. 
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    Free, publicly-accessible full text available December 1, 2024