More Like this

1. Who Will Win: Induced Pluripotent Stem Cells Versus Embryonic Stem Cells for β Cell Replacement and Diabetes Disease Modeling?

   https://doi.org/10.1007/s11892-018-1109-y  

   Jacobson, Elena F. ; Tzanakakis, Emmanuel S. ( December 2018 , Current Diabetes Reports)
2. Two distinct trophectoderm lineage stem cells from human pluripotent stem cells

   https://doi.org/10.1016/j.jbc.2021.100386  

   Mischler, Adam ; Karakis, Victoria ; Mahinthakumar, Jessica ; Carberry, Celeste K. ; San Miguel, Adriana ; Rager, Julia E. ; Fry, Rebecca C. ; Rao, Balaji M. ( January 2021 , Journal of Biological Chemistry)

   null (Ed.)
3. CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells: CRISPR/Cas9-Mediated Fluorescent Tagging of Proteins in Pluripotent Stem Cells

   https://doi.org/10.1002/cphg.52  

   Sharma, Arun ; Toepfer, Christopher N. ; Ward, Tarsha ; Wasson, Lauren ; Agarwal, Radhika ; Conner, David A. ; Hu, Johnny H. ; Seidman, Christine E. ( January 2018 , Current Protocols in Human Genetics)
4. The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells: PrP Controls Notch in Neural Stem/Progenitor Cells

   https://doi.org/10.1002/stem.2501  

   Martin-Lannerée, Séverine ; Halliez, Sophie ; Hirsch, Théo Z. ; Hernandez-Rapp, Julia ; Passet, Bruno ; Tomkiewicz, Céline ; Villa-Diaz, Ana ; Torres, Juan-Maria ; Launay, Jean-Marie ; Béringue, Vincent ; et al ( March 2017 , STEM CELLS)
5. Serum-Free Manufacturing of Mesenchymal Stem Cell Tissue Rings Using Human-Induced Pluripotent Stem Cells

   https://doi.org/10.1155/2019/5654324  

   Winston, Tackla S. ; Suddhapas, Kantaphon ; Wang, Chenyan ; Ramos, Rafael ; Soman, Pranav ; Ma, Zhen ( January 2019 , Stem Cells International)

   Combination of stem cell technology and 3D biofabrication approaches provides physiological similarity to in vivo tissues and the capability of repairing and regenerating damaged human tissues. Mesenchymal stem cells (MSCs) have been widely used for regenerative medicine applications because of their immunosuppressive properties and multipotent potentials. To obtain large amount of high-quality MSCs without patient donation and invasive procedures, we differentiated MSCs from human-induced pluripotent stem cells (hiPSC-MSCs) using serum-free E6 media supplemented with only one growth factor (bFGF) and two small molecules (SB431542 and CHIR99021). The differentiated cells showed a high expression of common MSC-specific surface markers (CD90, CD73, CD105, CD106, CD146, and CD166) and a high potency for osteogenic and chondrogenic differentiation. With these cells, we have been able to manufacture MSC tissue rings with high consistency and robustness in pluronic-coated reusable PDMS devices. The MSC tissue rings were characterized based on inner diameter and outer ring diameter and observed cell-type-dependent tissue contraction induced by cell-matrix interaction. Our approach of simplified hiPSC-MSC differentiation, modular fabrication procedure, and serum-free culture conditions has a great potential for scalable manufacturing of MSC tissue rings for different regenerative medicine applications. 

   more » « less