Mapping the spatiotemporal evolution of solute transport in articular cartilage explants reveals how cartilage recovers fluid within the contact area during sliding
- Award ID(s):
- 1635536
- PAR ID:
- 10076023
- Date Published:
- Journal Name:
- Journal of Biomechanics
- Volume:
- 71
- Issue:
- C
- ISSN:
- 0021-9290
- Page Range / eLocation ID:
- 271 to 276
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Cartilage exudes interstitial fluid and metabolic waste products during loading and recovers interstitial fluid and nutrients from the synovial fluid during articulation through mechanisms that remain unclear. Here, Moore et al illustrating a fundamentally new and unanticipated mechanism of fluid and nutrient uptake by articular cartilage. The results suggest that fluid entrained at the leading edge of contact is pressurized and subsequently forced back into the porous articular surface to restore hydration, thickness, nutrition and lubrication.more » « less
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