Malaria, mainly caused by
Developing selective enzyme inhibitors allows for the expansion of molecular toolboxes to investigate functions and activities of target enzymes. The histone acetyltransferase 1 (
- NSF-PAR ID:
- 10084502
- Publisher / Repository:
- Wiley-Blackwell
- Date Published:
- Journal Name:
- Chemical Biology & Drug Design
- Volume:
- 93
- Issue:
- 5
- ISSN:
- 1747-0277
- Page Range / eLocation ID:
- p. 865-873
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Abstract BACKGROUND As a soilborne fungus,
Fusarium oxysporum can cause vascular wilt in numerous economically important crops. Application of antifungal drugs is the primary method for the control ofF. oxysporum . Cyp51, a key enzyme of sterol biosynthesis is the main target of sterol demethylation inhibitors.RESULTS The
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