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Title: Methylene Blue-Catalyzed Oxidative Cleavage of N-Carbonylated Indoles
The development of a visible-light-mediated oxidative cleavage of electron-deficient indoles is reported. Methylene blue serves as an effective catalyst and the transformation shows a broad substrate scope. A variety of functional groups are well accommodated in the mild reaction conditions. The photo-mediated single electron transfer and oxidative cleavage mechanisms were investigated via density functional theory and Marcus theory calculations.  more » « less
Award ID(s):
1654122
PAR ID:
10089503
Author(s) / Creator(s):
; ; ; ;
Date Published:
Journal Name:
Synthesis
Volume:
50
Issue:
15
ISSN:
0039-7881
Page Range / eLocation ID:
2897 to 2907
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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