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Title: Coupling oligonucleotides possessing a poly-cytosine tag with magnetic ionic liquids for sequence-specific DNA analysis
Oligonucleotide probes were designed with a poly-cytosine region that facilitates stable anchoring to a magnetic ionic liquid support. By tethering a recognition sequence to the poly-C tag, the resulting diblock oligonucleotides distinguished single-nucleotide variants and captured DNA targets from interfering genomic DNA and cell lysate for qPCR amplification.  more » « less
Award ID(s):
1709372
NSF-PAR ID:
10108159
Author(s) / Creator(s):
; ; ; ; ; ; ;
Date Published:
Journal Name:
Chemical Communications
Volume:
54
Issue:
73
ISSN:
1359-7345
Page Range / eLocation ID:
10284 to 10287
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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