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Title: Rhodium/Gold Dual Catalysis in Carbene sp 2 C−H Functionalization/Conia‐ene Cascade for the Stereoselective Synthesis of Diverse Spirocarbocycles
Abstract

A Rh(II)/Au(I) catalyzed carbene cascade approach for the stereoselective synthesis of diverse spirocarbocycles is described. The cascade reaction involves a rhodium carbene initiatedsp2C−H functionalization followed by a gold catalyzed Conia‐ene cyclization. The cascade reaction accommodates a variety of aryl substituents as well as ring sizes and proceeds with high diastereoselectivity providing access to diverse spirocarbocycles.

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Award ID(s):
1753187
NSF-PAR ID:
10116047
Author(s) / Creator(s):
 ;  ;  ;  ;  
Publisher / Repository:
Wiley Blackwell (John Wiley & Sons)
Date Published:
Journal Name:
Advanced Synthesis & Catalysis
Volume:
361
Issue:
12
ISSN:
1615-4150
Page Range / eLocation ID:
p. 2951-2958
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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