The domino Michael/Michael reaction between ( E )-7-aryl-7-oxohept-5-enals and trans -cinnamaldehydes was investigated by using modularly designed organocatalysts (MDOs). It was found that both the enamine and iminium catalytic modes of the MDOs are switchable and can be individually switched on and off by using appropriate combinations of the precatalyst modules and the reaction conditions. When both the enamine and iminium catalysis modes of the MDOs are switched on, the desired domino reaction products can be obtained in good yields and stereoselectivities under optimized conditions.
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Michael–Michael Ring-Closure Reactions for a Dihapto-Coordinated Naphthalene Complex of Molybdenum
- Award ID(s):
- 1800051
- PAR ID:
- 10159562
- Date Published:
- Journal Name:
- Organometallics
- Volume:
- 39
- Issue:
- 8
- ISSN:
- 0276-7333
- Page Range / eLocation ID:
- 1404 to 1412
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Mike Shuler's career has touched the professional and personal lives of countless individuals. From the undergraduates who learned the fundamentals of bioprocess engineering and nanobiotechnology, to the graduate students who helped push knowledge boundaries across length scales, to the young faculty who learned the meaning of academia, Mike Shuler's patient and thoughtful mentorship built careers and inspired greatness. We are proud and humbled to collect the following personal reflections from a cross section of his Cornell colleagues and friends. So many individuals have been influenced by Mike Shuler's distinguished mentorship, and we hope that these personal and professional reflections adequately reflect our collective feelings toward him. A full categorization of Mike's Midas touch could fill volumes. We have tried, through the following pages, to capture and personify a career that is beyond measure, and that has contributed so much to his academic community and to society.more » « less
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