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   https://doi.org/10.1038/s43247-025-02558-w  

   Zarkogiannis, Stergios D; Rae, James W_B; Shipley, Benjamin R; Mortyn, P Graham (December 2025, Communications Earth & Environment)

   Abstract Planktonic foraminifera are key contributors to the oceanic carbon cycle. In pelagic environments, carbonate production by planktonic biomineralizers regulates ocean-atmosphere carbon dioxide exchange and exports surface carbon to the deep ocean. Here we compare shell traits of three planktonic foraminifera species from the central Atlantic with a suite of environmental parameters to discern the factors underlying their variations. Our analysis revealed that calcification in foraminifera is associated with seawater density and depends on species habitat depth, whereas foraminifera bulk shell densities may serve as a seawater density proxy, regardless of species. We observe that their shell weights increased with habitat depth, enabling the living cells to adjust their overall density to match that of the surrounding liquid. This suggests that calcification in nonmotile organisms has a buoyancy regulatory function and will respond to the anthropogenically driven reductions in ocean density (oceanic rarefication), with potential consequences for the carbon cycle. 

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2. DNA sequence influences hexasome orientation to regulate DNA accessibility

   https://doi.org/10.1093/nar/gkz283  

   Brehove, Matthew; Shatoff, Elan; Donovan, Benjamin T; Jipa, Caroline M; Bundschuh, Ralf; Poirier, Michael G (April 2019, Nucleic Acids Research)
3. microRNA-124 directly suppresses Nodal and Notch to regulate mesodermal development

   https://doi.org/10.1016/j.ydbio.2023.06.017  

   Konrad, Kalin D; Arnott, Malcolm; Testa, Michael; Suarez, Santiago; Song, Jia L (October 2023, Developmental Biology)
4. FERONIA functions through Target of Rapamycin (TOR) to negatively regulate autophagy

   https://doi.org/10.3389/fpls.2022.961096  

   Wang, Ping; Clark, Natalie M.; Nolan, Trevor M.; Song, Gaoyuan; Whitham, Olivia G.; Liao, Ching-Yi; Montes-Serey, Christian; Bassham, Diane C.; Walley, Justin W.; Yin, Yanhai; et al (August 2022, Frontiers in Plant Science)

   FERONIA (FER) receptor kinase plays versatile roles in plant growth and development, biotic and abiotic stress responses, and reproduction. Autophagy is a conserved cellular recycling process that is critical for balancing plant growth and stress responses. Target of Rapamycin (TOR) has been shown to be a master regulator of autophagy. Our previous multi-omics analysis with loss-of-function fer-4 mutant implicated that FER functions in the autophagy pathway. We further demonstrated here that the fer-4 mutant displayed constitutive autophagy, and FER is required for TOR kinase activity measured by S6K1 phosphorylation and by root growth inhibition assay to TOR kinase inhibitor AZD8055. Taken together, our study provides a previously unknown mechanism by which FER functions through TOR to negatively regulate autophagy. 

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5. Sulfated glycans engage the Ang–Tie pathway to regulate vascular development

   https://doi.org/10.1038/s41589-020-00657-7  

   Griffin, Matthew E.; Sorum, Alexander W.; Miller, Gregory M.; Goddard, William A.; Hsieh-Wilson, Linda C. (February 2021, Nature Chemical Biology)

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