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Title: Methods for studying the metabolic basis of Drosophila development: Drosophila developmental metabolism
Award ID(s):
1726633
NSF-PAR ID:
10181916
Author(s) / Creator(s):
;
Date Published:
Journal Name:
Wiley Interdisciplinary Reviews: Developmental Biology
Volume:
6
Issue:
5
ISSN:
1759-7684
Page Range / eLocation ID:
e280
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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    Flow cytometry estimates of genome sizes among species of Drosophila show a 3-fold variation, ranging from ∼127 Mb in Drosophila mercatorum to ∼400 Mb in Drosophila cyrtoloma. However, the assembled portion of the Muller F element (orthologous to the fourth chromosome in Drosophila melanogaster) shows a nearly 14-fold variation in size, ranging from ∼1.3 Mb to >18 Mb. Here, we present chromosome-level long-read genome assemblies for 4 Drosophila species with expanded F elements ranging in size from 2.3 to 20.5 Mb. Each Muller element is present as a single scaffold in each assembly. These assemblies will enable new insights into the evolutionary causes and consequences of chromosome size expansion.

     
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