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At any given moment, humans are bombarded with a constant stream of new information. But the brain can take in only a fraction of that information at once. So how does the brain decide what to pay attention to and what to ignore? Many laboratory studies of attention avoid this issue by simply telling participants what to attend to. But in daily life, people rarely receive instructions like that. Instead people must often rely on past experiences to guide their attention. When cycling close to home, for example, a person knows to watch out for the blind junction at the top of the hill and for the large pothole just around the corner. Günseli and Aly set out to bridge the gap between laboratory studies of attention and real-world experience by asking healthy volunteers to perform two versions of a task while lying inside a brain scanner. The task involved looking at pictures of rooms with different shapes. Each room also contained a different painting. In one version of the task, the volunteers were told to pay attention to either the paintings or to the room shapes. In the other version, the volunteers had to use previously memorized cues to work out for themselves whether they should focus on the paintings or on the shapes. The brain scans showed that two areas of the brain with roles in memory – the hippocampus and the prefrontal cortex – were involved in the task. Notably, both areas increased their activity when the volunteers used memory to guide their attention, compared to when they received instructions telling them what to focus on. Moreover, patterns of activity within the hippocampus and prefrontal cortex contained information about what the participants were about to focus on next – even before volunteers saw the particular picture that they were supposed to pay attention to. In the hippocampus, this was particularly the case when the volunteers based their decisions on memory. These results reveal a key way in which humans leverage memories of past experiences to help optimize future behavior. Understanding this process could shed light on why memory impairments make it harder for people to adjust their behavior to achieve specific goals.
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The Medial Temporal Lobe Is Critical for Spatial Relational Perception
The medial temporal lobe (MTL) is traditionally considered to be a system that is specialized for long-term memory. Recent work has challenged this notion by demonstrating that this region can contribute to many domains of cognition beyond long-term memory, including perception and attention. One potential reason why the MTL (and hippocampus specifically) contributes broadly to cognition is that it contains relational representations—representations of multidimensional features of experience and their unique relationship to one another—that are useful in many different cognitive domains. Here, we explore the hypothesis that the hippocampus/MTL plays a critical role in attention and perception via relational representations. We compared human participants with MTL damage to healthy age- and education-matched individuals on attention tasks that varied in relational processing demands. On each trial, participants viewed two images (rooms with paintings). On “similar room” trials, they judged whether the rooms had the same spatial layout from a different perspective. On “similar art” trials, they judged whether the paintings could have been painted by the same artist. On “identical” trials, participants simply had to detect identical paintings or rooms. MTL lesion patients were significantly and selectively impaired on the similar room task. This work provides further evidence that the hippocampus/MTL plays a ubiquitous role in cognition by virtue of its relational and spatial representations and highlights its important contributions to rapid perceptual processes that benefit from attention.
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- PAR ID:
- 10183076
- Date Published:
- Journal Name:
- Journal of Cognitive Neuroscience
- Volume:
- 32
- Issue:
- 9
- ISSN:
- 0898-929X
- Page Range / eLocation ID:
- 1780 to 1795
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
-
Accepted Manuscript
- Journal Article:
- https://doi.org/10.1162/jocn_a_01583
