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Title: Recommendations for Advancing Genome to Phenome Research in Non-Model Organisms
Synopsis The 2020 SICB Society-wide Symposium “Building Bridges from Genome to Phenome: Molecules, Methods and Models” brought together a diverse group of scientists to discuss recent progress in linking phenotype plasticity to changes at the level of the genome, epigenome, and proteome, while exploring the boundaries between variation and speciation. In a follow-up workshop, participants were asked to assess strengths and weaknesses of current approaches, to identify common barriers inhibiting their progress, and to outline the resources needed to overcome those barriers. Discussion groups generally recognized the absence of any overarching theoretical framework underlying current genome to phenome research and, therefore, called for a new emphasis on the development of conceptual models as well as the interdisciplinary collaborations needed to create and test those models. Participants also recognized a critical need for new and improved molecular and bioinformatic approaches to assist in describing function/phenotypes across phylogeny. Additionally, like all scientific endeavors, progress in genome to phenome research will be enhanced by improvements in science education and communication both within and among working groups.  more » « less
Award ID(s):
1927470 1922755
NSF-PAR ID:
10196272
Author(s) / Creator(s):
; ; ; ;
Date Published:
Journal Name:
Integrative and Comparative Biology
Volume:
60
Issue:
2
ISSN:
1540-7063
Page Range / eLocation ID:
397 to 401
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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