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Title: Viral Hacks of the Plant Vasculature: The Role of Phloem Alterations in Systemic Virus Infection
For plant viruses, the ability to load into the vascular phloem and spread systemically within a host is an essential step in establishing a successful infection. However, access to the vascular phloem is highly regulated, representing a significant obstacle to virus loading, movement, and subsequent unloading into distal uninfected tissues. Recent studies indicate that during virus infection, phloem tissues are a source of significant transcriptional and translational alterations, with the number of virus-induced differentially expressed genes being four- to sixfold greater in phloem tissues than in surrounding nonphloem tissues. In addition, viruses target phloem-specific components as a means to promote their own systemic movement and disrupt host defense processes. Combined, these studies provide evidence that the vascular phloem plays a significant role in the mediation and control of host responses during infection and as such is a site of considerable modulation by the infecting virus. This review outlines the phloem responses and directed reprograming mechanisms that viruses employ to promote their movement through the vasculature.  more » « less
Award ID(s):
1644713
PAR ID:
10213547
Author(s) / Creator(s):
; ; ;
Date Published:
Journal Name:
Annual Review of Virology
Volume:
7
Issue:
1
ISSN:
2327-056X
Page Range / eLocation ID:
351 to 370
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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