ABSTRACT The afterglow emission from gamma-ray bursts (GRBs) is believed to originate from a relativistic blast wave driven into the circumburst medium. Although the afterglow emission from radio up to X-ray frequencies is thought to originate from synchrotron radiation emitted by relativistic, non-thermal electrons accelerated by the blast wave, the origin of the emission at high energies (HE; ≳GeV) remains uncertain. The recent detection of sub-TeV emission from GRB 190114C by the Major Atmospheric Gamma Imaging Cherenkov Telescopes (MAGIC) raises further debate on what powers the very high energy (VHE; ≳300 GeV) emission. Here, we explore the inverse Compton scenario as a candidate for the HE and VHE emissions, considering two sources of seed photons for scattering: synchrotron photons from the blast wave (synchrotron self-Compton or SSC) and isotropic photon fields external to the blast wave (external Compton). For each case, we compute the multiwavelength afterglow spectra and light curves. We find that SSC will dominate particle cooling and the GeV emission, unless a dense ambient infrared photon field, typical of star-forming regions, is present. Additionally, considering the extragalactic background light attenuation, we discuss the detectability of VHE afterglows by existing and future gamma-ray instruments for a wide range of model parameters. Studying GRB 190114C, we find that its afterglow emission in the Fermi-Large Area Telescope (LAT) band is synchrotron dominated. The late-time Fermi-LAT measurement (i.e. t ∼ 104 s), and the MAGIC observation also set an upper limit on the energy density of a putative external infrared photon field (i.e. ${\lesssim} 3\times 10^{-9}\, {\rm erg\, cm^{-3}}$), making the inverse Compton dominant in the sub-TeV energies.
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Quantum approach for nanoparticle fluorescence by sub‐ns photon detection
Well defined detection and analysis of nanoparticle‐sized samples such as extracellular vesicles or viruses may be important for potential disease diagnostics. However, using conventional flow‐cytometry optical methods to evaluate such small particles is quite challenging. The reason is that the particle is smaller than the diffraction limit, making detection difficult. An alternative approach is fluorescence detection via conjugated fluorochromes attached to the nanoparticles; the challenge in this case is the limitation imposed upon detection of a very small number of emitted photons buried in high background photon counts. Emitted fluorescence is described by the well‐known equation kf = σa I Q, which describes the emitted fluorescence rate (kf) (photons/s) as the multiplication of molecular absorption cross section(σa), excitation intensity (I), and quantum yield (Q). In addition, the excitation rate is equal to 1/t, which is the inverse of the lifetime of several ns representing the most typical conjugated fluorescent molecules used in flow cytometry. We recently developed a sub‐ns photon sensor that is faster than most fluorescence lifetimes, since sub‐ns speed is a critically important parameter for the separation of individual emitted photons. Based on our observation of fluorescence and background levels on typical commercial flow cytometers it is evident that a significant component of the background is induced by water‐molecular vibrations. Therefore, understanding what constitutes all the components that contribute to the signals we measure in flow cytometry would help in defining what we currently call “background signals.” We attempted to define a theoretical model to try to unravel these issues. This model was based on use of a reflective dry surface in the absence of water molecules. Our objective was to determine if it is possible to minimize background and enhance signal, and to provide valuable information on the contributing components of the signals collected. In order to test this model, we tested a single dried particle 50 nm in diameter on a reflective surface with minimum background. While this is clearly not a standard biological system, our results suggest that this quantum approach closely follows established photon base theory. Our goal was to define the parameters for practical nanoparticle‐fluorescence analysis while enhancing our knowledge of the contribution of background properties.
more » « less- Award ID(s):
- 2013940
- NSF-PAR ID:
- 10453465
- Publisher / Repository:
- Wiley Blackwell (John Wiley & Sons)
- Date Published:
- Journal Name:
- Cytometry Part A
- Volume:
- 99
- Issue:
- 2
- ISSN:
- 1552-4922
- Page Range / eLocation ID:
- p. 145-151
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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Color centers in wide bandgap semiconductors are attracting broad attention for use as platforms for quantum technologies relying on room-temperature single-photon emission (SPE), and for nanoscale metrology applications building on the centers’ response to electric and magnetic fields. Here, we demonstrate room-temperature SPE from defects in cubic boron nitride (cBN) nanocrystals, which we unambiguously assign to the cubic phase using spectrally resolved Raman imaging. These isolated spots show photoluminescence (PL) spectra with zero-phonon lines (ZPLs) within the visible region (496–700 nm) when subject to sub-bandgap laser excitation. Second-order autocorrelation of the emitted photons reveals antibunching with
g2 (0) ∼ 0.2, and a decay constant of 2.75 ns that is further confirmed through fluorescence lifetime measurements. The results presented herein prove the existence of optically addressable isolated quantum emitters originating from defects in cBN, making this material an interesting platform for opto-electronic devices and quantum applications. -
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Semiconductor quantum dots embedded in micropillar cavities are excellent emitters of single photons when pumped resonantly. Often, the same spatial mode is used to both resonantly excite a quantum-dot state and to collect the emitted single photons, requiring cross polarization to reduce the uncoupled scattered laser light. This inherently reduces the source brightness to 50%. Critically, for some quantum applications the total efficiency from generation to detection must be over 50%. Here, we demonstrate a resonant-excitation approach to creating single photons that is free of any cross polarization, and in fact any filtering whatsoever. It potentially increases single-photon rates and collection efficiencies, and simplifies operation. This integrated device allows us to resonantly excite single quantum-dot states in several cavities in the plane of the device using connected waveguides, while the cavity-enhanced single-photon fluorescence is directed vertically (off-chip) in a Gaussian mode. We expect this design to be a prototype for larger chip-scale quantum photonics.
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Ultra-high-energy (UHE) photons are an important tool for studying the high-energy Universe. A plausible source of photons with exa-eV (EeV) energy is provided by UHE cosmic rays (UHECRs) undergoing the Greisen–Zatsepin–Kuzmin process (Greisen 1966; Zatsepin & Kuzmin 1966) or pair production process (Blumenthal 1970) on a cosmic background radiation. In this context, the EeV photons can be a probe of both UHECR mass composition and the distribution of their sources (Gelmini, Kalashev & Semikoz 2008; Hooper, Taylor & Sarkar 2011). At the same time, the possible flux of photons produced by UHE protons in the vicinity of their sources by pion photoproduction or inelastic nuclear collisions would be noticeable only for relatively near sources, as the attenuation length of UHE photons is smaller than that of UHE protons; see, for example, Bhattacharjee & Sigl (2000) for a review. 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Abstract Fluorescence lifetime measurements provide information about the fluorescence relaxation, or intensity decay, of organic fluorophores, fluorescent proteins, and other inorganic molecules that fluoresce. The fluorescence lifetime is emerging in flow cytometry and is helpful in a variety of multiparametric, single cell measurements because it is not impacted by nonlinearity that can occur with fluorescence intensity measurements. Yet time‐resolved cytometry systems rely on major hardware modifications making the methodology difficult to reproduce. The motivation of this work is, by taking advantage of the dynamic nature of flow cytometry sample detection and applying digital signal processing methods, to measure fluorescence lifetimes using an unmodified flow cytometer. We collect a new lifetime‐dependent parameter, referred to herein as the fluorescence‐pulse‐delay (FPD), and prove it is a valid representation of the average fluorescence lifetime. To verify we generated cytometric pulses in simulation, with light emitting diode (LED) pulsation, and with true fluorescence measurements of cells and microspheres. Each pulse is digitized and used in algorithms to extract an average fluorescence lifetime inherent in the signal. A range of fluorescence lifetimes is measurable with this approach including standard organic fluorophore lifetimes (∼1 to 22 ns) as well as small, simulated shifts (0.1 ns) under standard conditions (reported herein). This contribution demonstrates how digital data acquisition and signal processing can reveal time‐dependent information foreshadowing the exploitation of full waveform analysis for quantification of similar photo‐physical events within single cells. © 2014 The Authors. Published by Wiley Periodicals, Inc.
