The transport of Ca2+across membranes precedes the fusion and fission of various lipid bilayers. Yeast vacuoles under hyperosmotic stress become fragmented through fission events that requires the release of Ca2+stores through the TRP channel Yvc1. This requires the phosphorylation of phosphatidylinositol‐3‐phosphate (PI3P) by the PI3P‐5‐kinase Fab1 to produce transient PI(3,5)P2pools. Ca2+is also released during vacuole fusion upon
- Award ID(s):
- 1818310
- NSF-PAR ID:
- 10458058
- Publisher / Repository:
- Wiley-Blackwell
- Date Published:
- Journal Name:
- Traffic
- Volume:
- 21
- Issue:
- 7
- ISSN:
- 1398-9219
- Page Range / eLocation ID:
- p. 503-517
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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